IP Library Granted Patent US 10,067,087
Granted Patent B2
US 10,067,087 · App. 15/303,551 · Granted Sep 4, 2018

Biomolecule analyzer

Inventors: Shinichi Goto (Sakai, JP); Hideki Kinoshita (Sakai, JP); Mieko Hirabayashi (Sakai, JP); Kouhei Kageyama (Sakai, JP); Taiga Tominaga (Sakai, JP)
Assignee: SHARP LIFE SCIENCE CORPORATION
G01N27/44739G01N27/44704G01N27/44747G01N27/44726
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Quick Facts
Patent No.
US 10,067,087
App. No.
15/303,551
Granted
Sep 4, 2018
Kind
B2
Abstract

A biomolecule analyzer ( 100 ) includes an arm part ( 20 - 23, 66 ) retaining a transfer membrane ( 1 ) that is arranged at a position opposing a first opening ( 50 a ), and a drive unit ( 62 - 65 ) that is provided below an anode buffer tank ( 30 ), and drives the arm part in a substantially horizontal direction, in which the arm part passes along outer sides of side walls of the anode buffer tank ( 30 ), wraps around upper ends of the side walls and links at inner walls of the side wall.

Claims (35)

1. A biomolecule analyzer comprising:

a first buffer solution tank;

a second buffer solution tank that is disposed above the first buffer solution tank;

a separation unit in which a separation medium is stored, having a first opening that opens within the first buffer solution tank and a second opening that opens within the second buffer solution tank, and the separation unit is standing up in a substantially vertical direction;

an arm part that retains a transfer membrane disposed at a position opposing the first opening; and

a drive unit that is provided under the first buffer solution tank, and drives the arm part in a substantially horizontal direction,

wherein the arm part passes along outer sides of side walls of the first buffer solution tank, wraps around upper ends of the side walls, and links at inner sides of the side walls.

2. The biomolecule analyzer according to claim 1 ,

wherein the transfer membrane has a first end that is forward in a movement direction of the arm part and a second end that is rearward in the movement direction of the arm part, and

wherein the arm part includes a first fixing part that fixes the first end, a second fixing part that fixes the second end, and an elastic body that biases the first fixing part and the second fixing part in directions facing away from each other.

3. The biomolecule analyzer according to claim 2 ,

wherein a support member for supporting the transfer membrane from an opposite side of the transfer membrane to the separation unit is provided at a bottom part of the first buffer solution tank, and

wherein the transfer membrane is bent by the separation unit so that an opposite side to the separation unit becomes convex.

4. The biomolecule analyzer according to claim 3 , wherein the support member is on the bottom part and includes a pair of members interposing a position opposing the first opening.

5. The biomolecule analyzer according to claim 1 ,

wherein the transfer membrane has a first end that is forward in a movement direction of the arm part, and a second end that is rearward in the movement direction of the arm part, and

wherein the arm part includes a first fixing part that fixes the first end, a second fixing part that fixes the second end, and a connection part that connects the first fixing part and the second fixing part to be separated by a predetermined distance.

6. The biomolecule analyzer according to claim 5 , wherein the connection part includes a pair of parts disposed at positions to interpose the transfer membrane laterally relative to the movement direction of the arm part.

7. The biomolecule analyzer according to claim 1 ,

wherein a support member that supports the transfer membrane from an opposite side to the separation unit of the transfer membrane is provided to a bottom part of the first buffer solution tank, and

wherein the transfer membrane is bent by the separation unit so that an opposite side to the separation unit becomes convex.

8. The biomolecule analyzer according to claim 7 , wherein the support member includes a pair of members respectively on the bottom part to interpose a position that opposes the first opening.

9. The biomolecule analyzer according to claim 8 , wherein a slope angle of the transfer membrane from a position contacting the support member until a position contacting the first opening is at least 14 and no more than 60 downwards relative to a horizontal plane.

10. The biomolecule analyzer according to claim 1 ,

wherein a portion of the arm part that wraps around the upper ends of the side walls is detachable from the drive unit, and

wherein the first buffer solution tank is detachable from the biomolecule analyzer.

11. The biomolecule analyzer according to claim 10 , wherein the arm part is linked to the drive unit, and has a first portion extending at outer sides of the side walls until a position aligning with upper ends of the side walls, and a second portion that fits with the first portion, and extends to an inner side of the side walls by spanning the upper ends of the side walls.

12. The biomolecule analyzer according to claim 1 ,

wherein the first buffer solution tank, the second buffer solution tank and the separation unit are transparent.

13. The biomolecule analyzer according to claim 1 , wherein a first electrode is disposed in the first buffer solution tank,

wherein a second electrode is disposed in the second buffer solution tank, and

wherein the transfer membrane is disposed so as to be interposed between the first opening and the first electrode.

14. The biomolecule analyzer according to claim 1 ,

wherein the separation unit is mounted to be detachable from the second buffer solution tank, and

wherein the second buffer solution tank is mounted to be detachable from the first buffer solution tank.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2019
From: SHARP LIFE SCIENCE CORPORATION
To: MERCK LTD.
Reel/Frame 048514/0614 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2017
From: SHARP KABUSHIKI KAISHA
To: SHARP LIFE SCIENCE CORPORATION
Reel/Frame 043100/0818 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 12, 2016
From: GOTO, SHINICHI; KINOSHITA, HIDEKI; HIRABAYASHI, MIEKO; KAGEYAMA, KOUHEI; TOMINAGA, TAIGA
To: SHARP KABUSHIKI KAISHA
Reel/Frame 039995/0188 →
Priority Claims (1)
JP 2014-235992 · Nov 20, 2014 · national
Continuity (1)
Related Publication 20170038336A1 · Feb 9, 2017