Device and method for simulating chemosensation of smoking
A device for simulating a chemosenzation of smoking includes an outer layer, a porous medium and a chemesthetic agent. The porous medium is disposed within the outer layer. The chemesthetic agent is disposed within the porous medium and activates a TRP channel.
1. A device for simulating a chemosensation of smoking, comprising:
a chemesthetic agent that activates a TRP channel, the chemesthetic agent including at least one of Zingiberaceae extract, Brassicaceae extract, Toddalioidae extract and Lamiaceae extract; and
an atomizer configured to volatize the chemesthetic agent, wherein
the agent is disposed in a propylene glycol based solution, and
the propylene glycol based solution includes a stabilizing constituent that includes at least one of a Benzoin resin from the Styracaceae family, sandalwood, red cedarwood, vetiver, orris root, oakmoss and myrrh.
2. The device according to claim 1 , wherein the glycol based solution includes ethanol.
3. The device according to claim 1 , wherein the TRP channel is a TRP receptor that imparts a chemesthetic sensation.
4. The device according to claim 1 , wherein the device is sized and shaped to mimic a cigarette.
5. The device according to claim 1 , wherein the agent is a volatile agent.
6. The device according to claim 1 , wherein the TRP channel is one or more of TRPV1, TRPA1, TRPV3 and TRPM8.
7. The device according to claim 1 , wherein the agent includes Zingiberaceae extract.
8. The device according to claim 1 , wherein the agent includes Brassicaceae extract.
9. The device according to claim 1 , wherein the agent includes Toddalioidae extract.
10. The device according to claim 1 , wherein the agent includes Lamiaceae extract.
11. The device according to claim 1 , wherein the agent includes at least one of the following:
approximately 5-10% by weight Szechuan pepper extract, 5-10% by weight mustard seed extract, approximately 5-10% by weight allspice extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 30-50% by weight galangal extract, approximately 5-10% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution;
approximately 15-25% by weight Szechuan pepper extract, approximately 15-25% by weight mustard extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 15-25% by weight galangal extract, approximately 10-15% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution; and
approximately 15-25% by weight Szechuan pepper extract, approximately 5-10% by weight mustard extract, approximately 5-10% allspice extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 15-25% by weight galangal extract, approximately 10-15% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution.
12. The device according to claim 1 , wherein the agent includes approximately 10-15% by weight benzoin resin extract.
13. A device for simulating a chemosensation of smoking, comprising:
a chemesthetic agent that activates a TRP channel disposed within the porous medium, the chemesthetic agent including at least one of 6-paradol, isothiocyanate, hydroxy-α-sanshool, 1′-acetoxychavicol, camphor, eugenol and thymol; and
an atomizer configured to volatize the chemesthetic agent, wherein
the agent is disposed in a propylene glycol based solution, and
the propylene glycol based solution includes a stabilizing constituent that includes at least one of a Benzoin resin from the Styracaceae family, sandalwood, red cedarwood, vetiver, orris root, oakmoss and myrrh.
14. The device according to claim 13 , wherein the propylene glycol based solution includes ethanol.
15. The device according to claim 13 , wherein the agent activates a TRP channel that is a TRP receptor that imparts a chemesthetic sensation.
16. The device according to claim 13 , wherein the TRP channel is one or more of TRPV1, TRPA1, TRPV3 and TRPM8.
17. The device according to claim 13 , wherein the agent includes 6-paradol.
18. The device according to claim 13 , wherein the agent includes 1′-acetoxychavicol.
19. The device according to claim 13 , wherein the agent includes isothiocyanate.
20. The device according to claim 13 , wherein the agent includes hydroxy-α-asanshool.
21. The device according to claim 13 , wherein the agent includes camphor.
22. The device according to claim 13 , wherein the agent includes thymol.
23. The device according to claim 13 , wherein the agent includes at least one of the following:
approximately 5-10% by volume hydroxy-α-sanshool solution, 5-10% by volume isothiocyanates solution, approximately 5-10% by volume eugenol solution, approximately 15-25% by volume 6-paradol solution, approximately 30-50% by volume 1′-acetoxychavicol solution, approximately 5-10% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution;
approximately 15-25% by volume hydroxy-α-sanshool solution, approximately 15-25% by volume isothiocyanate solution, approximately 15-25% by volume 6-paradol solution, approximately 15-25% by volume 1′-acetoxychavicol solution, approximately 10-15% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution; and
approximately 15-25% by volume hydroxy-α-sanshool solution, approximately 5-10% by volume isothiocyanate solution, approximately 5-10% by volume eugenol solution, approximately 15-25% by volume 6-paradol solution, approximately 15-25% 1′-acetoxychavicol solution, approximately 10-15% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution.
24. The device according to claim 13 , wherein the agent includes a stabilizing constituent of approximately 5-15% by volume.
25. A composition for simulating a chemosensation of smoking, comprising:
a chemesthetic agent that activates a TRP channel disposed in a propylene glycol based solution, the chemesthetic agent including at least one of Zingiberaceae extract, Brassicaceae extract, Toddalioidae extract, Lamiaceae extract, 6-paradol, isothiocyanate, hydroxy-α-sanshool, 1′-acetoxychavicol, camphor, eugenol and thymol, wherein
the agent includes approximately 10-15% by weight benzoin resin extract, and
the propylene glycol based solution includes a stabilizing constituent that includes at least one of a Benzoin resin from the Styracaceae family, sandalwood, red cedarwood, vetiver, orris root, oakmoss and myrrh.
26. The composition according to claim 25 , wherein the glycol based solution includes ethanol.
27. The composition according to claim 25 , wherein the TRP channel is a TRP receptor that imparts a chemesthetic sensation.
28. The composition according to claim 25 , wherein the agent is a volatile agent.
29. The composition according to claim 25 , wherein the TRP channel is one or more of TRPV1, TRPA1, TRPV3 and TRPM8.
30. The composition according to claim 25 , wherein the agent includes Zingiberaceae extract.
31. The composition according to claim 25 , wherein the agent includes Brassicaceae extract.
32. The composition according to claim 25 , wherein the agent includes Toddalioidae extract.
33. The composition according to claim 25 , wherein the agent includes Lamiaceae extract.
34. The composition according to claim 25 , wherein the agent includes 6-paradol.
35. The composition according to claim 25 , wherein the agent includes 1′-acetoxychavicol.
36. The composition according to claim 25 , wherein the agent includes isothiocyanate.
37. The composition according to claim 25 , wherein the agent includes hydroxy-α-sanshool.
38. The composition according to claim 25 , wherein the agent includes camphor.
39. The composition according to claim 25 , wherein the agent includes thymol.
40. The composition according to claim 25 , wherein the agent includes at least one of the following:
approximately 5-10% by weight Szechuan pepper extract, 5-10% by weight mustard seed extract, approximately 5-10% by weight allspice extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 30-50% by weight galangal extract, approximately 5-10% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution;
approximately 15-25% by weight Szechuan pepper extract, approximately 15-25% by weight mustard extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 15-25% by weight galangal extract, approximately 10-15% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution;
approximately 15-25% by weight Szechuan pepper extract, approximately 5-10% by weight mustard extract, approximately 5-10% allspice extract, approximately 15-25% by weight Aframomum Melegueta extract, approximately 15-25% by weight galangal extract, approximately 10-15% by weight rosemary extract, and approximately 0.2-0.4% by volume thymol solution;
approximately 5-10% by volume hydroxy-α-sanshool solution, 5-10% by volume isothiocyanates solution, approximately 5-10% by volume eugenol solution, approximately 15-25% by volume 6-paradol solution, approximately 30-50% by volume 1′-acetoxychavicol solution, approximately 5-10% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution;
approximately 15-25% by volume hydroxy-α-sanshool solution, approximately 15-25% by volume isothiocyanate solution, approximately 15-25% by volume 6-paradol solution, approximately 15-25% by volume 1′-acetoxychavicol solution, approximately 10-15% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution; and
approximately 15-25% by volume hydroxy-α-sanshool solution, approximately 5-10% by volume isothiocyanate solution, approximately 5-10% by volume eugenol solution, approximately 15-25% by volume 6-paradol solution, approximately 15-25% 1′-acetoxychavicol solution, approximately 10-15% by volume camphor solution, and approximately 0.2-0.4% by volume thymol solution.