Microcapsules produced from blended sol-gel precursors and method for producing the same
The present invention features microcapsule particles with an oil or aqueous liquid core, and shell composed of a blend of metal or semi-metal oxide polymers. Methods for preparing and using the microcapsule particles in personal care, therapeutic, cosmetic and cosmeceutic products are also provided.
1. A microcapsule particle composition comprising:
(a) a core formed from an oil containing at least one active ingredient; (b) a shell encapsulating said core, wherein said shell is composed of
(i) at least one hydrolyzable silicon oxide polymer, and
(ii) at least one silicon oxide polymer having a non-hydrolyzable substituent; and
(c) a surfactant,
wherein the at least one hydrolyzable silicon oxide polymer is formed from a silicon alkoxide having a formula of Si(OR) 4 , in which —OR is C 1 -C 18 alkoxy or aryloxy group that is hydrolyzable upon dispersion in water, the weight ratio of polymer of (i) to the polymer of (ii) ranges from 199:1 to 9:1, the polymer of (ii) is present in an amount up to 10% of the total weight of the shell, the at least one active ingredient is present in an amount between 50 and 90 weight percent of the microcapsule on a dry basis, and the surfactant is an oleth-10-phosphate present in an amount of 0.1% to 5% by weight of the microcapsule particle composition.
2. The microcapsule particle composition of claim 1 , wherein the at least one silicon oxide polymer having a non-hydrolyzable substituent is dimethyldiethoxysilane, n-octylmethyldiethoxysilane, poly(diethoxysiloxane) or hexadecyltriethoxysilane.
3. A personal care, therapeutic, cosmetic or cosmeceutic product comprising the microcapsule particle composition of claim 1 .
4. A process for the preparation of the microcapsule particle composition of claim 1 containing an oil core, the process comprising:
(a) combining, in a sol-gel process:
(i) an emulsion containing an oil; and
(ii) a mixture of at least one hydrolyzable sol-gel precursor and at least one sol-gel precursor having at least one non-hydrolyzable substituent, wherein the at least one sol-gel precursor having at least one non-hydrolyzable substituent is present in an amount of up to 10% of the total sol-gel precursor of (ii);
(b) curing the product of step (a); and
(c) adding a surfactant to the product of step (b), thereby preparing microcapsule particles containing an oil core, in which the surfactant is an oleth-10-phosphate present in an amount of 0.1% to 5% by weight of the microcapsule particle composition,
wherein the at least one hydrolyzable sol-gel precursor is a hydrolyzable silicon alkoxide having a formula of Si(OR) 4 , in which —OR is a C 1 -C 18 alkoxy group or aryloxy group that is hydrolyzable upon dispersion in water, the sol-gel precursor having at least one non-hydrolyzable substituent is a silicon oxide precursor having at least one non-hydrolyzable substituent, the weight ratio of the hydrolyzable sol-gel precursor and the sol-gel precursor having at least one non-hydrolyzable substituent ranges from 199:1 to 9:1.
5. The process of claim 4 , wherein the oil comprises at least one active ingredient.
6. The process of claim 5 , wherein the active ingredient is a fragrance oil.
7. The process of claim 6 , wherein the fragrance oil is mixed with an emulsifier.
8. The process of claim 4 , wherein the sol-gel precursor having at least one non-hydrolyzable substituent is dimethyldiethoxysilane, n-octylmethyldiethoxysilane, hexadecyltriethoxysilane diethyldiethoxysilane, 1,1,3,3-tetraethoxy-1,3-dimethyldisiloxane, or poly(diethoxysiloxane).
9. The process of claim 4 , wherein the silicon alkoxide is tetramethyl orthosilicate, tetraethyl orthosilicate or tetrapropyl orthosilicate.
10. The process of claim 4 , wherein the product of step (a) is cured at room temperature.
11. The process of claim 4 , wherein the product of step (a) is cured at 30° C. to 70° C.
12. The process of claim 4 , wherein the mixture of (ii) is a neat mixture of the at least one hydrolyzable sol-gel precursor and at least one sol-gel precursor having at least one non-hydrolyzable substituent.
13. The process of claim 4 , wherein the mixture of (ii) is an emulsion of the at least one hydrolyzable sol-gel precursor and at least one sol-gel precursor having at least one non-hydrolyzable substituent.
14. The process of claim 4 , wherein the mixture of (ii) is added drop-wise to the emulsion of (i).
15. A process for the preparation of the microcapsule particle composition of claim 1 containing an oil core, the process comprising:
(a) mixing, in a sol-gel process
(i) a first emulsion containing an oil and at least one sol-gel precursor having at least one non-hydrolyzable substituent; and
(ii) a second emulsion containing at least one hydrolyzable sol-gel precursor, wherein the at least one sol-gel precursor of (i) is present in an amount of up to 10% of the total sol-gel precursor of (i) and (ii);
(b) curing the mixture; and
(c) adding a surfactant to the product of step (b), thereby preparing microcapsule particles containing an oil core, in which the surfactant is an oleth-10-phosphate present in an amount of 0.1% to 5% by weight of the microcapsule particle composition,
wherein the at least one hydrolyzable sol-gel precursor is a hydrolyzable silicon alkoxide having a formula of Si(OR) 4 , in which —OR is a C 1 -C 18 alkoxy group or aryloxy group that is hydrolyzable upon dispersion in water, the sol-gel precursor having at least one non-hydrolyzable substituent is a silicon oxide precursor having at least one non-hydrolyzable substituent, the weight ratio of the hydrolyzable sol-gel precursor and the sol-gel precursor having at least one non-hydrolyzable substituent ranges from 199:1 to 9:1.
16. The process of claim 15 , wherein the oil comprises at least one active ingredient.
17. The process of claim 15 , wherein the sol-gel precursor of (i) is dimethyldiethoxysilane, n-octylmethyldiethoxysilane, hexadecyltriethoxysilane, diethyldiethoxysilane, 1,1,3,3-tetraethoxy-1,3-dimethyldisiloxane, or poly(diethoxysiloxane).
18. The process of claim 15 , wherein the silicon alkoxide is tetramethyl orthosilicate, tetraethyl orthosilicate or tetrapropyl orthosilicate.
19. The process of claim 15 , wherein the mixture is cured at room temperature.
20. The process of claim 15 , wherein the mixture is cured at 30° C. to 70° C.
21. A process for the preparation of the microcapsule particle composition of claim 1 containing an oil core, the process comprising:
(a) mixing an oil with
(i) at least one sol-gel precursor having at least one non-hydrolyzable substituent; and
(ii) at least one hydrolyzable sol-gel precursor, wherein the at least one sol-gel precursor of (i) is present in an amount of up to 10% of the total sol-gel precursor of (i) and (ii);
(b) cooling the mixture of (a) to room temperature;
(c) adding the mixture of (a) to an emulsifier solution to produce a second mixture;
(d) homogenizing the second mixture of (c) to produce a homogenized mixture;
(e) adding a defoamer to the homogenized mixture of (d);
(f) curing the product of (e), and
(g) adding a surfactant to the product of step (f), thereby preparing microcapsule particles containing an oil or aqueous liquid core, in which the surfactant is an oleth-10-phosphate present in an amount of 0.1% to 5% by weight of the microcapsule particle composition,
wherein the at least one hydrolyzable sol-gel precursor is a hydrolyzable silicon alkoxide having a formula of Si(OR) 4 , in which —OR is a C 1 -C 18 alkoxy group or aryloxy group that is hydrolyzable upon dispersion in water, the sol-gel precursor having at least one non-hydrolyzable substituent is a silicon oxide precursor having at least one non-hydrolyzable substituent, the weight ratio of the hydrolyzable sol-gel precursor and the sol-gel precursor having at least one non-hydrolyzable substituent ranges from 199:1 to 9:1.
22. The process of claim 21 , wherein the oil comprises at least one active ingredient.
23. The process of claim 21 , wherein the active ingredient is a fragrance.
24. The process of claim 21 , wherein the sol-gel precursor of (i) is dimethyldiethoxysilane, n-octylmethyldiethoxysilane, hexadecyltriethoxysilane, diethyldiethoxysilane, 1,1,3,3-tetraethoxy-1,3-dimethyldisiloxane, or poly(diethoxysiloxane).
25. The process of claim 21 , wherein the silicon alkoxide is tetramethyl orthosilicate, tetraethyl orthosilicate or tetrapropyl orthosilicate.
26. The process of claim 21 , wherein the mixture is cured at room temperature.
27. The process of claim 21 , wherein the mixture is cured at 30° C. to 70° C.
28. A microcapsule particle composition comprising:
(a) a core formed from an oil or aqueous liquid containing at least one active ingredient; and
(b) a shell encapsulating said core, wherein said shell is composed of
(i) at least one hydrolyzable silicon oxide polymer, and
(ii) at least one silicon oxide polymer having a non-hydrolyzable substituent; and
(c) a surfactant, in which the surfactant is an oleth-10-phosphate present in an amount of 0.1% to 5% by weight of the microcapsule particle composition,
wherein the polymer of (ii) is present in an amount up to 5% of the total weight of the shell and the microcapsule particle comprises between 50 and 90 weight percent of the at least one active ingredient on a dry basis,
wherein the at least one hydrolyzable sol-gel precursor is a hydrolyzable silicon alkoxide having a formula of Si(OR) 4 , in which —OR is a C 1 -C 18 alkoxy group or aryloxy group that is hydrolyzable upon dispersion in water, the sol-gel precursor having at least one non-hydrolyzable substituent is a silicon oxide precursor having at least one non-hydrolyzable substituent, the weight ratio of the hydrolyzable sol-gel precursor and the sol-gel precursor having at least one non-hydrolyzable substituent ranges from 199:1 to 9:1.
29. The microcapsule particle composition of claim 28 , wherein the oleth-10-phosphate is present in an amount of 0.1% to 5% by weight of the microcapsule particle composition, and the weight ratio of the hydrolyzable sol-gel precursor and the sol-gel precursor having at least one non-hydrolyzable substituent ranges from 199:1 to 19:1.
30. The microcapsule particle composition of claim 28 , wherein the oleth-10-phosphate is present in an amount of 0.1% to 0.2% by weight of the microcapsule particle composition.
31. The microcapsule particle composition of claim 28 , wherein the microcapsule particle composition is in the powder form.
32. A consumer product comprising a microcapsule composition of claim 1 .
33. The consumer product of claim 32 , wherein the consumer product is a personal care product, a personal cleaning product, a shampoo, a hair rinse, a body wash, a soap, an anti-perspirant, a deodorant, a shampoo powder, a deodorant powder, a foot powder, a soap powder, a baby powder, a wash-off product, a laundry product, a powdered detergent, a liquid detergent, a fabric conditioner, a liquid dish detergent, an automatic dish detergent, a dryer sheet, a household cleaning dry wipe, a powder dish detergent, or a floor cleaning cloth.
34. A consumer product comprising a microcapsule particle composition of claim 28 .
35. The consumer product of claim 34 , wherein the consumer product is a personal care product, a personal cleaning product, a shampoo, a hair rinse, a body wash, a soap, an anti-perspirant, a deodorant, a shampoo powder, a deodorant powder, a foot powder, a soap powder, a baby powder, a wash-off product, a laundry product, a powdered detergent, a liquid detergent, a fabric conditioner, a liquid dish detergent, an automatic dish detergent, a dryer sheet, a household cleaning dry wipe, a powder dish detergent, or a floor cleaning cloth.