IP Library Granted Patent US 10,100,328
Granted Patent B2
US 10,100,328 · App. 14/968,235 · Granted Oct 16, 2018

Corn plant event MON87460 and compositions and methods for detection thereof

Inventors: Kim A. Beazley (St. Louis, MO); Paolo Castiglioni (St. Louis, MO); Mark A. Dizigan (St. Louis, MO); Rebecca A. Kelly (St. Louis, MO); John A. Korte (St. Louis, MO); Amanda Rock (St. Louis, MO); Christine Voyles (St. Louis, MO)
Assignee: Monsanto Technology LLC
C12N15/8273C12N15/1034C12N15/8261C12Q1/6895A01H1/04C12Q2600/13C12Q2600/158
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Quick Facts
Patent No.
US 10,100,328
App. No.
14/968,235
Granted
Oct 16, 2018
Kind
B2
Abstract

The present invention provides a transgenic corn event MON87460, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for MON87460 in a sample, methods for detecting the presence of MON87460 event polynucleotides in a sample, and probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of MON87460 in a sample. The present invention also provides methods of breeding with MON87460 to produce water deficit tolerance corn plants.

Claims (18)

1. A progeny transgenic corn plant derived from a transgenic-corn plant event designated MON87460, representative seed of said corn plant event having been deposited under ATCC Accession No. PTA-8910, wherein said progeny transgenic corn plant has a chromosome that comprises SEQ ID NO: 1 and SEQ ID NO:2.

2. The progeny transgenic corn plant of claim 1 , wherein said plant has a chromosome comprising SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO:7, SEQ ID NO:25, or SEQ ID NO:24.

3. The progeny transgenic corn plant of claim 1 , wherein said progeny transgenic plant is water deficit tolerant.

4. The progeny corn plant of claim 3 , wherein said corn plant exhibits increased grain yield under water-limited conditions in comparison to a control corn plant.

5. A method of producing corn plant seed containing a heterologous transgene insert that confers water deficit tolerance to a plant, said method comprising crossing a water deficit tolerant first parent corn plant comprising SEQ ID NO: 1, a heterologous transgenic insert comprising a truncated rice actin promoter that is operably linked to a cspB gene, and SEQ ID NO:2 with a second parent corn plant, wherein either the first or second parent corn plant is the female parent of the cross, and harvesting seed that comprise SEQ ID NO: 1, and the heterologous transgenic insert, and SEQ ID NO:2 from the female parent, thereby producing corn plant seed containing a heterologous transgene insert that confers water deficit tolerance to a plant.

6. The method of claim 5 , wherein said first and second corn plants are inbred plants and wherein hybrid corn seed is produced.

7. The method of claim 5 , wherein said insert comprises SEQ ID NO:7 or SEQ ID NO:24.

8. A method of detecting the presence of genomic DNA from a transgenic corn plant event designated MON87460 or progeny thereof in a corn tissue sample, the method comprising:

contacting the sample comprising DNA with a probe that hybridizes under stringent hybridization conditions with genomic DNA from the corn plant event MON87460 and does not hybridize under the stringent hybridization conditions with genomic DNA from a control corn plant, wherein said stringent hybridization conditions comprise 0.2× sodium chloride/sodium citrate (SSC) at 50° C. and wherein said probe is substantially homologous or complementary to SEQ ID NO: 1 or SEQ ID NO:2, representative seed of said corn plant event 87460 having been deposited under ATCC Accession No. PTA-8910; and

subjecting the sample and probe to stringent hybridization conditions; and

detecting hybridization of the probe to DNA from the sample, thereby detecting SEQ ID NO: 1 or SEQ ID NO:2 in the corn tissue sample.

9. A method for obtaining a water deficit tolerant corn plant that lacks an intact selectable marker gene comprising the steps of:

exposing a corn plant containing a chromosome comprising SEQ ID NO: 1, a heterologous transgene insert, and SEQ ID NO:2 to one or more recombination-inducing agents, wherein said heterologous transgene insert comprises a selectable marker gene and a truncated rice actin promoter that is operably linked to a cspB gene;

selecting a corn plant comprising SEQ ID NO: 1, a truncated rice actin promoter that is operably linked to a cspB gene, and SEQ ID NO:2, wherein said selectable marker gene or a portion thereof has been eliminated or disrupted, thereby obtaining a water deficit tolerant corn plant that lacks an intact selectable marker gene.

10. The method of claim 9 , wherein said recombination-inducing agent comprises a recombinase, a nuclease, a homologous replacement sequence, a non-homologous replacement sequence, or a combination thereof.

11. The method of claim 10 , wherein said homologous replacement sequence or said non-homologous replacement sequence comprises one or more genes.

12. The method of claim 9 , wherein said heterologous transgene insert comprises SEQ ID NO: 7 or SEQ ID NO: 24.

13. A method for obtaining corn yield stability in at least two locations under water-limiting conditions, comprising the steps of growing a plurality of progeny corn plants of claim 1 in said locations under said water deficit conditions and harvesting grain from said plants, wherein yield of the harvested grain is improved in comparison to control corn plants at both locations.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2016
From: BEAZLEY, KIM A.; CASTIGLIONI, PAOLO; DIZIGAN, MARK A.; KELLY, REBECCA A.; KORTE, JOHN ALAN; ROCK, AMANDA; VOYLES, CHRISTINE
To: MONSANTO TECHNOLOGY LLC
Reel/Frame 038422/0193 →
Continuity (4)
Continuation 13866651 · Apr 19, 2013
Division 12919845
Provisional Application 61032568 · Feb 29, 2008
Related Publication 20160168586A1 · Jun 16, 2016