Triazolo[4,5-D] pyramidine derivatives and their use as purine receptor antagonists
Compounds of formula (I) that are capable of acting as purine receptor antagonists, pharmaceutical compositions including the compounds, and methods of making the compounds, are disclosed. The compounds and compositions can be used in treating or preventing disorders related to purine receptor hyperfunctioning.
1. A method for forming a compound of formula
comprising the step of reacting a compound of formula
and a compound of formula
in the presence of a base.
2. The method of claim 1 , wherein the base is sodium hydride, triethylamine, N,N-diisopropylethylamine, or potassium carbonate.
3. The method of claim 1 , wherein the method comprises the step of forming the compound of formula
by reacting a compound of formula
and a compound of formula
in the presence of a base.
4. The method of claim 3 , wherein the base is sodium hydride or potassium tert-butoxide.
5. The method of claim 1 , wherein the compound of formula is a compound of formula