Infusion catheter and method of use
An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed.
1. An infusion catheter comprising:
an elongate flexible shaft comprising a wall and a lumen extending a length between a proximal end and a distal end;
a sealing member within the shaft lumen comprising a wall and a lumen extending a length between a proximal end and a distal end, the distal end of the sealing member being attached to the distal end of the shaft;
a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens and connecting to a distal end cap; and
a plurality of eluting arms, each eluting arm having a lumen fluidly connected to the distal end of the shaft lumen, extending radially around the central axis member, and connecting to the distal end cap.
2. The infusion catheter of claim 1 , further comprising a frame having a plurality of tines, each tine within the lumen of each eluting arm.
3. The infusion catheter of claim 2 , wherein the frame is constructed from a shape memory material.
4. The infusion catheter of claim 3 , wherein the shape memory material forms a spiral shape.
5. The infusion catheter of claim 3 , wherein the shape memory material forms a pear shape.
6. The infusion catheter of claim 1 , wherein each eluting arm comprises a plurality of infusion ports fluidly connected to the lumen of each eluting arm.
7. The infusion catheter of claim 6 , wherein each eluting arm is positioned within an outer tube having a surface comprising a plurality of infusion ports fluidly connected to a lumen, a closed proximal end, and a closed distal end.
8. The infusion catheter of claim 7 , wherein the surface of each outer tube is less porous than each eluting arm.
9. The infusion catheter of claim 1 , wherein each eluting arm comprises a porous surface.
10. The infusion catheter of claim 9 , wherein the porous surface elutes pressurized fluid from each eluting arm lumen.
11. The infusion catheter of claim 9 , wherein the porous surface is constructed from a material selected from the group consisting of: polytetrafluoroethylene (PTFE), expanded PTFE (ePTFE), Tyvek, and Kynar polyvinylidene fluoride (PVDF).
12. The infusion catheter of claim 1 , wherein the inner diameter of the sealing member lumen and the outer diameter of the central axis member are dimensioned such that central axis member slip fits within the sealing member lumen with a close clearance permitting movement in the central axis member while preventing fluid leakage through the close clearance.
13. The infusion catheter of claim 12 , wherein the central axis member is slidable through the sealing member lumen and the shaft lumen, the shaft lumen having a fluid pressure higher than a fluid pressure outside of the shaft lumen, without leaking fluid through the close clearance.
14. The infusion catheter of claim 1 , wherein the distance between the distal end cap and the distal end of the shaft is reversibly shortened by sliding central axis member through the sealing member lumen, thereby expanding the plurality of eluting arms away from the central axis member.
15. The infusion catheter of claim 1 , wherein the central axis member comprises a guidewire lumen.
16. An infusion system kit comprising:
the infusion catheter of claim 1 ; and
a guidewire configured for insertion through a guidewire lumen of the central axis member.