IP Library Granted Patent US 10,123,896
Granted Patent B2
US 10,123,896 · App. 15/123,094 · Granted Nov 13, 2018

Apparatus and methods of inducing weight loss using blood flow control

Inventors: Gianrico Farrugia (Rochester, MN); Paul A. Friedman (Rochester, MN); Elizabeth Rajan (Rochester, MN); Charles J. Bruce (South Ponte Vedra Beach, FL); Samuel J. Asirvatham (Rochester, MN); Michael J. Levy (Rohester, MN); Louis-Michel Wong Kee Song (Rochester, MN); Juliane Bingener-Casey (Rochester, MN); Navtej S. Buttar (Rochester, MN)
Assignee: Mayo Foundation for Medical Education and Research
A61F5/0013A61B5/026A61B5/03A61B5/4205A61B5/4238A61B17/12013A61B18/1492A61B18/1815A61F7/123A61N1/0556A61N1/36007A61B2017/00818A61B2018/00404A61B2018/00577A61B2018/00613A61F2007/126
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Quick Facts
Patent No.
US 10,123,896
App. No.
15/123,094
Granted
Nov 13, 2018
Kind
B2
Abstract

Methods and apparatus for inducing weight loss using blood flow control are described herein. The apparatus and methods operate by controlling blood flow to the stomach and/or small bowel.

Claims (21)

1. A method of inducing weight loss, the method comprising:

making a determination that a patient is ingesting food; and

reducing blood flow to the gastrointestinal tract after making the determination that a patient is ingesting food, wherein reducing blood flow to the gastrointestinal tract comprises cooling an exterior surface of one or more blood vessels that supply the stomach and/or small bowel.

2. A method according to claim 1 , wherein making a determination that a patient is ingesting food comprises one or more of: sensing distention of the patient's stomach, sensing increased pressure in the patient's stomach, sensing swallowing by the patient, receiving direct feedback from the user, and Doppler flow measurements to measure flow velocity.

3. A method according to claim 1 , wherein reducing blood flow to the gastrointestinal tract comprises mechanically constricting one or more blood vessels that supply the stomach and/or small bowel.

4. A method according to claim 1 , wherein cooling an exterior surface of one or more blood vessels that supply the stomach and/or small bowel comprises coiling a cooling device around the one or more blood vessels that supply the stomach and/or small bowel.

5. A method of inducing weight loss, the method comprising:

making a determination that a patient is ingesting food; and

reducing blood flow to the gastrointestinal tract after making the determination that a patient is ingesting food, wherein reducing blood flow to the gastrointestinal tract comprises cooling blood flowing through one or more blood vessels supplying blood to the stomach and/or the small bowel.

6. A method according to claim 5 , wherein the cooling comprises locating a perfusion balloon in a blood vessel and supplying cooling fluid within the perfusion balloon to reduce the temperature of blood flowing through the blood vessel past the perfusion balloon.

7. A method according to claim 1 , wherein reducing blood flow to the gastrointestinal tract comprises:

sensing an increase in blood flow in one or more gastric supply blood vessels; and

diverting flow away from the one or more blood vessels that supply the stomach and/or small bowel after sensing the increase in blood flow in the one or more blood vessels that supply the stomach and/or small bowel.

8. A method according to claim 1 , wherein reducing blood flow to the gastrointestinal tract comprises eluting a drug to reduce flow through one or more blood vessels that supply the stomach and/or small bowel.

9. A method according to claim 1 , wherein reducing blood flow to the gastrointestinal tract comprises expanding one or more blood vessels that do not supply the stomach and/or small bowel.

10. A method according to claim 1 , wherein reducing blood flow to the gastrointestinal tract comprises reducing the flow of blood away from the gastrointestinal tract.

11. A method of inducing weight loss, the method comprising:

making a determination that a patient is ingesting food; and

reducing blood flow to the gastrointestinal tract after making the determination that a patient is ingesting food, wherein reducing blood flow to the gastrointestinal tract comprises cooling one or more of: stomach, small bowel, and nerves associated with the stomach and/or small bowel.

12. A method according to claim 5 , wherein making a determination that a patient is ingesting food comprises one or more of: sensing distention of the patient's stomach, sensing increased pressure in the patient's stomach, sensing swallowing by the patient, receiving direct feedback from the user, and Doppler flow measurements to measure flow velocity.

13. A method according to claim 11 , wherein making a determination that a patient is ingesting food comprises one or more of: sensing distention of the patient's stomach, sensing increased pressure in the patient's stomach, sensing swallowing by the patient, receiving direct feedback from the user, and Doppler flow measurements to measure flow velocity.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2017
From: FARRUGIA, GIANRICO; FRIEDMAN, PAUL A.; RAJAN, ELIZABETH; BRUCE, CHARLES J.; ASIRVATHAM, SAMUEL J.; LEVY, MICHAEL J.; WONG KEE SONG, LOUIS-MICHEL; BINGENER-CASEY, JULIANE; BUTTAR, NAVTEJ S.
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 041619/0310 →
Continuity (2)
Provisional Application 61949024 · Mar 6, 2014
Related Publication 20170105860A1 · Apr 20, 2017
Cited By (3)
US 12,408,974 US 12,478,806 US 12,539,167