Charge steering high density electrode array

1. A deep brain stimulating device, comprising:

a semiconductor substrate;

an array of electrodes coupled to the semiconductor substrate, wherein each electrode is operable to function as at least one of an anode, a cathode, a float, and a common independent of other electrodes in the array, wherein the common is a specified voltage between the anode and the cathode; and

circuitry operable to control the array of electrodes, wherein the electrodes of the array are spatially arranged such that the circuitry is operable to selectively activate each electrode with a specified voltage to produce a unique electrical charge distribution across multiple electrodes that is steered to a targeted brain region, wherein the steered electrical charge distribution is voltage-based, the circuitry comprising a shift register associated with each electrode and operable to control each electrode, wherein an electric field is operable to be delivered in an asymmetrical pattern relative to a longitudinal axis or lateral axis of the deep brain stimulating device.

2. The device of claim 1 , wherein each electrode is further operable to selectively function as the cathode, the float, and the common, wherein each electrode further includes a digital circuit comprising an anode switch, cathode switch, common switch each operable to selectively function the associated electrode as at least one of the cathode, the float, and the common.

3. The device of claim 2 , wherein the digital circuit of each electrode comprises a single input and a clock, wherein each electrode is controlled by the single input and the clock.

4. The device of claim 3 , wherein the circuitry comprises a signal line and a clock line, wherein the signal line is coupled to the single input of each electrode and wherein the clock line is coupled to the clock of each electrode, such that the signal line and the clock line controls all electrodes, thereby passing contact state down the shift register.

5. The device of claim 3 , wherein the digital circuit of each electrode comprises a pair of latches operable to switch the associated electrode as at least one of the cathode, the float, and the common.

6. The device of claim 5 , wherein each switch comprises an AND gate, an inverter, and a transmission gate, wherein signals from the pair of latches are passed through the AND gate of each switch, and inverted by the associated inverter to control the associated transmission gate, such that only one AND gate is active at a given time to activate the selected at least one of the anode switch, cathode switch, and common switch.

7. The device of claim 1 , wherein the semiconductor substrate includes at least two surfaces and each surface includes at least two columns of electrodes and at least two rows of electrodes.

8. The device of claim 1 , wherein the array of electrodes includes from about 50 to about 25,000 electrodes.

9. The device of claim 1 , wherein the array of electrodes includes from about 5000 to about 15,000 electrodes.

10. The device of claim 1 , wherein the array of electrodes includes greater than 25,000 electrodes.

11. The device of claim 1 , wherein the semiconductor substrate includes at least two surfaces that are perpendicular to one another, wherein each of the two surfaces includes a portion of the array of electrodes.

12. The device of claim 11 , wherein the semiconductor substrate is formed into a plus shape having eight perpendicularly opposed surfaces, wherein each of the eight perpendicularly opposed surfaces includes a portion of the array of electrodes.

13. The device of claim 1 , wherein the semiconductor substrate includes the circuitry operable to control the array of electrodes, wherein the shift register comprises a continuous shift register operable to serially control the array of electrodes.

14. A deep brain stimulating system using the deep brain stimulating device of claim 1 , comprising:

the deep brain stimulating device of claim 1 ;

an implanted pulse generator; and

an electrical connection extension electrically coupling the circuitry of the deep brain stimulating device to the implanted pulse generator.

15. The device of claim 1 , wherein the semiconductor substrate includes four wafer sections formed into a plus shape, wherein the four wafer sections are comprised of a pair of vertical wafers planarly coupled together and defining a front groove, and a pair of horizontal wafers planarly coupled together and defining a rear groove, wherein the pair of vertical wafers and the pair of horizontal wafers are coupled to each other via the front and rear grooves to form the plus shape.

16. The device of claim 1 , wherein the circuitry comprises a signal line and a clock line, wherein the signal line is coupled to a single input of each electrode and wherein the clock line is coupled to a clock of each electrode, such that the signal line and the clock line controls all electrodes, thereby passing contact state down the shift register.

17. The device of claim 1 , wherein the shift register comprises a bistable multivibrator.

18. The device of claim 1 , wherein the shift register comprises a continuous shift register operable to serially control the array of electrodes.

19. A method of stimulating a neural region in vivo, comprising identifying a region of neural tissue to be electrically stimulated, wherein the region of neural tissue has a three dimensional area;

inserting the deep brain stimulating device of claim 1 into a location in proximity to the region of neural tissue; and

delivering an electric field from the deep brain stimulating device that substantially matches the three dimensional area of the region of neural tissue.

20. The method of claim 19 , wherein the location in proximity to the region of neural tissue is in a portion of the three dimensional area.

21. The method of claim 19 , wherein the electric field is delivered in an asymmetrical pattern relative to a longitudinal axis or lateral axis of the deep brain stimulating device.

22. The method of claim 19 , wherein delivering the electric field from the deep brain stimulating device that substantially matches the three dimensional area of the region of neural tissue further comprises:

delivering the electric field from the deep brain stimulating device that estimates the three dimensional area of the region of neural tissue;

measuring the electric field from the deep brain stimulating device relative to the region of neural tissue; and

adjusting the electric field of the deep brain stimulating device to substantially match the three dimensional area of the region of neural tissue.

23. The method of claim 19 , wherein delivering the electric field from the deep brain stimulating device that substantially matches the three dimensional area of the region of neural tissue further comprises:

delivering the electric field from the deep brain stimulating device that estimates the three dimensional area of the region of neural tissue;

evaluating the effect of the electric field from the deep brain stimulating device; and

adjusting the electric field of the deep brain stimulating device based on the effect to minimize adverse side effects of the electric field.

24. The method of claim 19 , futher comprising controlling each electode with a single input and a clock of a digital circuit of the associated electrode, and selecting each electrode to function as at least one of the cathode, the float, and the common, wherein the digital circuit of each electrode includes an anode switch, cathode switch, common switch.

25. A deep brain stimulating device, comprising:

a semiconductor substrate;

an array of electrodes coupled to the semiconductor substrate, wherein each electrode includes a digital circuit comprising an anode switch, cathode switch, common switch each operable to selectively function the associated electrode as at least one of the cathode, the float, and the common, and wherein the digital circuit further comprises a single input and a clock, such that each electrode is controlled by the single input and the clock; and

circuitry operable to control the array of electrodes and comprising a signal line and a clock line, wherein the signal line is coupled to the single input of each electrode and wherein the clock line is coupled to the clock of each electrode, such that the signal line and the clock line controls all electrodes, thereby passing contact state down a shift register, wherein the electrodes of the array are spatially arranged such that the circuitry is operable to selectively activate each electrode with a specified voltage to produce a unique electrical charge distribution across multiple electrodes that is steered to a targeted brain region, wherein the steered electrical charge distribution is voltage-based.

26. The device of claim 25 , wherein the digital circuit of each electrode comprises a pair of latches operable to switch the associated electrode as at least one of the cathode, the float, and the common.

27. The device of claim 25 , wherein the semiconductor substrate includes four wafer sections formed into a plus shape, wherein the four wafer sections are comprised of a pair of vertical wafers planarly coupled together and defining a front groove, and a pair of horizontal wafers planarly coupled together and defining a rear groove, wherein the pair of vertical wafers and the pair of horizontal wafers are coupled to each other via the front and rear grooves to form the plus shape.