Compositions including
Topical compositions, packaging systems and methods for improving the appearance of skin or at least one sign of aging in skin including Kachnar are described.
1. A method of stimulating or increasing Quinone Reductase activity in a skin cell in a subject in need thereof comprising applying to the skin a composition in a cosmetically effective amount sufficient to stimulate or increase Quinone Reductase activity in the skin, wherein the composition comprises:
a. a plant ingredient or plant extract from Bauhinia , individually or in combination with an amount of a plant ingredient or plant extract from Sesamum , the amounts, individually or in combination capable of stimulating or increasing Quinone Reductase activity; and
b. at least one pharmaceutically or cosmetically acceptable vehicle.
2. The method of claim 1 , wherein the composition further comprises at least one DNA repair enzyme.
3. The method of claim 2 , where the at least one DNA repair enzyme is a pyrimidine glycosylate/abasic lyase.
4. The method of claim 2 , wherein the at least one DNA repair enzyme is selected from the group consisting of a bacteriophage T4 pyrimidine dimer-specific endonuclease, a Micrococcus luteus N-glycosylase/AP lyase, a Saccharomyces cerevisiae N-glycosylase/apurinic-apyrimidinic lyase, a Schizosaccharomyces pombe UV damage endonuclease (UVDE), a Chlorella virus isolate PBCV-I pyrimidine dimer-specific glycosylase, an Anacystis nidulans photolyase, and combinations thereof.
5. The method of claim 1 , wherein the composition is in a product form selected from the group consisting of an aerosol, a cream, a emulsion, a solid, a liquid, a dispersion, a foam, a gel, a lotion, a mousse, an ointment, a powder, a patch, a pomade, a solution, a pump a spray, a stick, a towelette, and combinations thereof.
6. The method of claim 1 , wherein the at least one pharmaceutically or cosmetically acceptable vehicle comprises one or more ingredients selected from the group consisting of water, a glycerin, a Cl -C4 alcohol, a fatty alcohol, a fatty ether, a fatty ester, a polyol, a glycol, a vegetable oil, a mineral oil, a liposome, a laminar lipid material, a silicone oil, and combinations thereof.
7. The method of claim 1 , wherein the composition has a substantially neutral pH.
8. The method of claim 1 , wherein the composition further comprises a skin whitening agent selected from the group consisting of tyrosinase inhibitors, free radical scavengers, and mixtures thereof.
9. The method of claim 1 , wherein the amount of Bauhinia , individually or in combination with a plant ingredient or plant extract from Sesamum , ranges from about 0.0001% to 5% by weight of the total composition.
10. The method of claim 1 , wherein the amount of Bauhinia , individually or in combination with a plant ingredient or plant extract from Sesamum , ranges from about 0.001% to about 0.5% by weight of the total composition.
11. The method of claim 1 , wherein the amount of Bauhinia , individually or in combination with a plant ingredient or plant extract from Sesamum , ranges from about 0.01% to about 0.1% by weight of the total composition.