Tissue engineered devices and methods for making same
Tissue engineered constructs and methods for fabricating the disclosed constructs are provided. Some of the disclosed tissue engineered constructs are designed to fill a void in the body due to surgical resection, for example from mastectomy or lumpectomy, wounds and the like. Some disclosed constructs comprise one or more projections designed to mimic the appearance of a structural feature when implanted into a host.
1. A volume forming unit (VFU) comprising endothelial channels, adipocytes and at least one projection, wherein the at least one projection is designed to simulate at least one structural feature of a nipple.
2. The VFU of claim 1 , wherein a second projection is designed to simulate the at least one structural feature of an areola and the second projection circumscribes the at least one projection designed to simulate at least one structural feature of a nipple.