IP Library Granted Patent US 10,166,328
Granted Patent B2
US 10,166,328 · App. 14/289,848 · Granted Jan 1, 2019

Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system

Inventors: Meriyan Oruklu (Chicago, IL); Timothy L. Ruchti (Gurnee, IL); Paul T. Kotnik (Commerce Township, MI); Anatoly S. Belkin (Glenview, IL)
Assignee: ICU Medical, Inc.
A61M5/142A61M5/1684A61M5/365A61M2205/18A61M2205/332A61M2205/3331A61M2205/3334A61M2205/3368
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Quick Facts
Patent No.
US 10,166,328
App. No.
14/289,848
Granted
Jan 1, 2019
Kind
B2
Abstract

In one step of a method for infusing an infusion fluid, the infusion fluid is pumped through a fluid delivery line of an infusion system. In another step, measurements are taken with at least one sensor connected to the infusion system. In an additional step, an air determination is determined with at least one processor. The air determination is related to air in the fluid delivery line. The air determination is based on the measurements taken by the at least one sensor. The air determination is further based on: (1) medication information regarding the infusion fluid or infusion information regarding the infusion of the infusion fluid; or (2) multi-channel filtering of the measurements from the at least one sensor or non-linear mapping of the measurements from the at least one sensor; and statistical process control charts applied to the multi-channel filtered measurements or applied to the non-linear mapped measurements.

Claims (23)

1. An infusion system configured to be connected to a fluid delivery line and to an infusion container containing an infusion fluid, the infusion system comprising:

a pump for pumping infusion fluid from the infusion container;

at least one force sensor connected to the pump or the fluid delivery line, the at least one force sensor configured to measure force on a plunger of the pump;

at least one processor in electronic communication with the pump and the at least one force sensor;

a memory in electronic communication with the at least one processor, the memory comprising programming code for execution by the at least one processor; and

wherein the programming code is configured to cause the at least one processor to:

estimate future derived force measurement based on an application of a Kalman filter on the measured force on the plunger, wherein the estimation of future derived force measurement comprises at least one of:

determine a mean force measurement based on the measured force;

determine a variance force measurement based on the measured force; and

determine a derivative force measurement based on the measured force;

calculate a residual between the future derived force measurement and the measured force;

construct a cumulative sum control chart based on the calculated residual; and

determine air in the fluid delivery line based on the cumulative sum control chart and volume of infusion fluid pumped from the infusion container.

2. An infusion method comprising:

pumping infusion fluid from an infusion container to a fluid delivery line;

measuring force on a plunger from a force sensor connected to a pump comprising the plunger or the fluid delivery line;

estimating future derived force measurements based on an application of a Kalman filter on the measured force on the plunger, wherein the estimation of the future derived force measurement comprises at least one of:

determining a mean force measurement based on the measured force;

determining a variance force measurement based on the measured force; and

determining a derivative force measurement based on the measured force;

calculating a residual between the future derived force measurement and the measured force;

constructing a cumulative sum control chart based on the calculated residual; and

determining air in the fluid delivery line based on the cumulative sum control chart and volume of infusion fluid pumped from the infusion container.

Assignments (3)
SECURITY AGREEMENT Recorded Mar 31, 2022
From: ICU MEDICAL, INC.
To: WELLS FARGO BANK, NATIONAL ASSOCIATION
Reel/Frame 059618/0412 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2017
From: HOSPIRA, INC.
To: ICU MEDICAL, INC.
Reel/Frame 041672/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 29, 2014
From: ORUKLU, MERIYAN, MRS.; RUCHTI, TIMOTHY L., MR.; KOTNIK, PAUL T., MR.; BELKIN, ANATOLY S., MR.
To: HOSPIRA, INC.
Reel/Frame 032987/0174 →
Continuity (2)
Provisional Application 61828522 · May 29, 2013
Related Publication 20140358077A1 · Dec 4, 2014
Cited By (27)
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