IP Library › Granted Patent US 10,172,537
Granted Patent B2
US 10,172,537 · App. 14/710,734 · Granted Jan 8, 2019

Rod-shaped body

Inventors: Joachim-Georg Pfeffer (Aachen, DE); Rolf W. Günther (Aachen, DE); Thomas Schmitz Rode (Aachen, DE)
Assignee: MARVIS INTERVENTIONAL GMBH
A61B5/055A61L29/126A61L29/18A61L31/026A61L31/048A61L31/125A61L31/18A61M25/09A61M2025/09133
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Quick Facts
Patent No.
US 10,172,537
App. No.
14/710,734
Granted
Jan 8, 2019
Kind
B2
Abstract

The invention relates to a rod-shaped body comprised of one or more filaments and of a non-ferromagnetic matrix material. The matrix material surrounds the filament(s) and/or adheres them to one another. The rod-shaped body is also comprised of a dopant consisting of particles that generate magnetic resonance tomographic artifacts that is introduced into the matrix material. Rod-shaped bodies of this type can be used to construct guide wires, catheters and other instruments to be used in minimally invasive surgical interventions.

Claims (62)

1. A rod-shaped body for manufacturing a medical instrument comprising:

one or more non-metallic filaments; and

a non-ferromagnetic matrix material consisting essentially of epoxy resin and a multiplicity of doping particles, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments, wherein the multiplicity of doping particles are distributed in the non-ferromagnetic matrix material, and wherein the doping particles generate magnetic resonance tomography artefacts.

2. The rod-shaped body according to claim 1 , wherein the medical instrument is a catheter or a guidewire.

3. The rod-shaped body according to claim 1 , wherein the one or more non-metallic filaments consist of plastic and/or glass fibre.

4. The rod-shaped body according to claim 1 wherein the doping particles are included continuously along the longitudinal axis of the rod-shaped body.

5. The rod-shaped body according to claim 1 , wherein the doping particles are included discontinuously along the longitudinal axis of the rod shaped body.

6. The rod-shaped body according to claim 1 , wherein the one or more non-metallic filaments are arranged in parallel.

7. The rod-shaped body according to claim 1 , wherein the one or more non-metallic filaments are braided with each other, woven, cross-linked, twisted or coiled.

8. The rod-shaped body according to claim 1 , wherein a single particle of the multiplicity of doping particles has a mass in the range of micrograms to nanograms and, due to a minimal amount in relation to the non-ferromagnetic matrix material, does not substantially influence outer shape, stability or torquing characteristics of the rod-shaped body.

9. The rod-shaped body according to claim 1 , having a diameter in the range of between 0.005 mm and 5 mm or between 0.1 and 1 mm.

10. The rod-shaped body according to claim 1 , wherein the doping particles do not substantially influence outer shape, stability or torquing characteristics.

11. The rod-shaped body according to claim 1 , wherein the rod-shaped body has a substantially smooth surface.

12. A guidewire consisting of:

at least one rod-shaped body consisting essentially of:

one or more non-metallic filaments;

a non-ferromagnetic matrix material, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments; and

a multiplicity of doping particles distributed in the non-ferromagnetic matrix material, wherein the doping particles generate magnetic resonance tomography artefacts; and

a non-ferromagnetic shell material, wherein the shell material encloses and/or agglutinates the at least one rod-shaped body.

13. The guidewire according to claim 12 consisting of several rod-shaped bodies having the same diameter or different diameters.

14. The guidewire according to claim 12 consisting of several rod-shaped bodies where a first rod-shaped body of the at least one rod-shaped body is surrounded with at least one secondary rod-shaped body of the at least one rod-shaped body having a smaller diameter.

15. The guidewire according to claim 14 , wherein the at least one secondary rod-shaped body is braided, woven, cross-linked, twisted or coiled around the first rod-shaped body.

16. The guidewire according to claim 12 , consisting of several different rod-shaped bodies wherein the different rod-shaped bodies possess different magnetic resonance tomography properties.

17. The guidewire according to claim 12 having an outer surface and wherein the outer surface is covered with a hydrophilic coating.

18. The guidewire according to claim 12 , wherein the non-ferromagnetic matrix material comprises epoxy resin.

19. A catheter consisting of:

at least one rod-shaped body, consisting essentially of:

one or more non-metallic filaments;

a non-ferromagnetic matrix material, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments; and

a multiplicity of doping particles distributed in the non-ferromagnetic matrix material, wherein the doping particles generate magnetic resonance tomography artefacts; and

a non-ferromagnetic shell material, wherein the shell material encloses and/or agglutinates the at least one rod-shaped body.

20. The catheter according to claim 19 , consisting of several rod-shaped bodies that are peripherally embedded in a radial distribution in the catheter.

21. The catheter according to claim 20 , wherein the rod-shaped bodies are embedded in a regular radial distribution.

22. The catheter according to claim 19 , consisting of several rod-shaped bodies wherein the rod-shaped bodies have the same or different diameters.

23. The catheter according to claim 19 , consisting of several rod-shaped bodies wherein the rod-shaped bodies are braided with each other, woven, cross-linked, twisted or coiled.

24. The catheter according to claim 19 , consisting of several different rod-shaped bodies wherein the different rod-shaped bodies possess different magnetic resonance tomography properties.

25. The catheter according to claim 19 , having an outer surface wherein the outer surface is covered with a hydrophilic coating.

26. A cylindrical composite body comprising a multiplicity of rod-shaped bodies used for manufacturing a magnetic resonance tomography (MRT)-compatible medical instrument, wherein at least one of the rod-shaped bodies is comprised of:

one or more non-metallic filaments;

a non-ferromagnetic matrix material, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments; and

doping particles distributed in the non-ferromagnetic matrix material, wherein the doping particles generate magnetic resonance tomography (MRT) artefacts thereby forming a doped matrix material

wherein each of the doping particles has a mass in the range of micrograms to nanograms, wherein the multiplicity of rod-shaped bodies have the same diameters, different diameters, or a first rod-shaped body of the multiplicity of rod-shaped bodies is surrounded by several secondary rod-shaped bodies of smaller diameters, and wherein the multiplicity of rod-shaped bodies is surrounded by a non-doped shell material.

27. The cylindrical composite body according to claim 26 wherein the medical instrument is a catheter or a guidewire.

28. The cylindrical composite body according to claim 26 wherein the one or more non-metallic filaments consists of plastic and/or glass fibre.

29. The cylindrical composite body according to claim 26 wherein the non-ferromagnetic matrix material consists of epoxy resin.

30. The cylindrical composite body according to claim 26 wherein at least one of the rod-shaped bodies is continuously doped along its longitudinal axis with said doping particles.

31. The cylindrical composite body according to claim 26 wherein at least one of the rod-shaped bodies is discontinuously doped along its longitudinal axis, in sections, with said doping particles.

32. The cylindrical composite body according to claim 26 wherein the one or more non-metallic filaments are arranged in parallel.

33. The cylindrical composite body according to claim 26 , consisting of several non-metallic filaments, wherein the non-metallic filaments are braided with each other, woven, cross-linked, twisted or coiled.

34. The cylindrical composite body according to claim 26 wherein the doping particles do not substantially influence outer shape, stability or torquing characteristics of the multiplicity of rod-shaped bodies.

35. The cylindrical composite body according to claim 26 wherein a diameter of the rod shaped-bodies is in the range of between 0.005 mm and 5 mm or in in the range of between 0.1 and 1 mm.

36. A cylindrical composite body comprising a multiplicity of rod-shaped bodies, wherein at least one of the rod-shaped bodies is comprised of

one or more non-metallic filaments,

a non-ferromagnetic matrix material, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments; and

doping particles included in the non-ferromagnetic matrix material, wherein the doping particles generate magnetic resonance tomography (MRT) artefacts thereby forming the doped matrix material, wherein each of the doping particles has a mass in the range of micrograms to nanograms, wherein the multiplicity of rod-shaped bodies have the same diameters or different diameters or a first rod-shaped body of the multiplicity of rod-shaped bodies is surrounded by several secondary rod-shaped bodies of smaller diameters, and wherein the multiplicity of rod-shaped bodies is surrounded by a non-doped shell material.

37. A guidewire consisting of:

at least one rod-shaped body comprising:

one or more non-metallic filaments;

a non-ferromagnetic matrix material, wherein the non-ferromagnetic matrix material encloses and/or agglutinates the one or more non-metallic filaments; and

a multiplicity of doping particles distributed in the non-ferromagnetic matrix material, wherein the doping particles generate magnetic resonance tomography artefacts; and

a non-ferromagnetic shell material, wherein the shell material encloses and/or agglutinates the at least one rod-shaped body,

wherein a first rod-shaped body of the at least one rod-shaped body is surrounded with at least one secondary rod-shaped body of the at least one rod-shaped body having a smaller diameter.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2017
From: DURING, KLAUS, DR.
To: MARVIS INTERVENTIONAL GMBH
Reel/Frame 041643/0524 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 13, 2017
From: MARVIS TECHNOLOGIES GMBH
To: MARVIS MEDICAL GMBH
Reel/Frame 041558/0450 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 9, 2017
From: DURING, KLAUS, DR.
To: MARVIS TECHNOLOGIES GMBH
Reel/Frame 041518/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 8, 2017
From: MARVIS MEDICAL GMBH
To: DURING, KLAUS, DR.
Reel/Frame 041506/0211 →
Priority Claims (1)
DE 10 2005 030 472 · Jun 28, 2005 · national
Continuity (2)
Continuation In Part 11993658
Related Publication 20150245783A1 · Sep 3, 2015
Cited By (3)
US 12,636,118 US 12,697,470 US 12,721,933