Oral care compositions
An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.
1. A high water oral care composition comprising
an orally acceptable carrier comprising from 10% to 90% water,
from 0.05 to 10% by weight zinc phosphate,
from 0.01% to 5% by weight stannous fluoride,
from 0.1% to 6% by weight arginine or lysine, and
from 0.1 to 5.0% by weight of an organic acid buffer system selected from citric acid, lactic acid, malic acid, maleic acid, fumaric acid, acetic acid, succinic acid, and tartaric acid, measured as the combined amount of organic acid and any conjugate base salt;
wherein all amounts are based upon the total weight of the composition.
2. A composition according to claim 1 , wherein the zinc phosphate is a preformed salt of zinc phosphate.
3. A composition according to claim 1 , wherein the amount of the water is 10% by weight or more, relative to the weight of the oral care composition.
4. A composition according claim 1 , wherein the organic buffer system comprises a carboxylic acid and one or more conjugate base salts thereof, for example, alkali metal salts thereof.
5. A composition according to claim 4 , wherein the one or more conjugate base salts are independently selected from sodium and potassium salts, or combinations thereof.
6. A composition according to claim 4 , wherein the acid is citric acid, and the one or more conjugate base salts comprise monosodium citrate (monobasic), disodium citrate (dibasic), trisodium citrate (tribasic), and combinations thereof.
7. A composition according to claim 1 , wherein the buffer system comprises citric acid and a sodium citrate salt, in a ratio of from 1:3 to 1:6.
8. A composition according to claim 1 , wherein the composition comprises arginine or lysine at about 1.5% by wt.
9. A composition according to claim 1 , wherein the composition comprises arginine.
10. A composition according to claim 1 , wherein the composition comprises lysine.
11. A composition according to claim 1 , further comprising an effective amount of one or more alkali phosphate salts.
12. A composition according to claim 10 , wherein the alkali phosphate salts comprise tetrasodium pyrophosphate or tetrapotassium pyrophosphate, optionally in an amount of 0.5 to 5% by weight of the composition.
13. A composition according to claim 10 , wherein the alkali phosphate salts comprise sodium tripolyphosphate or potassium tripolyphosphate, optionally in an amount of 0.5 to 6% by weight of the composition.
14. A composition according to claim 1 , further comprising one or more sources of zinc ions in addition to the zinc phosphate, for example, a zinc salt selected from zinc citrate, zinc oxide, zinc lactate, zinc pyrophosphate, zinc sulfate, or zinc chloride.
15. A composition according to claim 1 , wherein the oral care composition is a dentifrice.
16. A method of treatment or prevention of erosive tooth demineralization, gingivitis, plaque, and/or dental caries, the method comprising the application to the oral cavity of a person in need thereof a composition according to claim 1 .