Trace elements
The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium and which comprises a concentration of the metal(s) of at least 60 mg/ml. The solution further comprises at least one compound selected from the group comprising iodine, potassium iodide, sodium iodide, iron, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA and sodium hydroxide. The trace element solution is prepared by a method consisting essentially of the steps of preparing a MnCO 3 mixture in a container; adding an EDTA/NaOH mixture to the container and subsequently adding at least one metal compound; and adding Na 2 SeO 3 to the container to obtain the trace element solution. The method also comprises the step of adding CrCl 3 .6H 2 O to the trace element solution.
1. An injectable trace element solution, said solution comprising:
(a) 5 to 10 mg/ml selenium;
(b) 35-50 mg/ml zinc;
(c) manganese; and
(d) iron,
wherein a total concentration of selenium, zinc, manganese and iron in the solution is at least 60 mg/ml.
2. The solution of claim 1 , further comprising at least one of iodine, potassium iodide, sodium iodide, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA or sodium hydroxide.
3. A solution as claimed in claim 2 , in which at least one of the metal(s) is provided in the form of an EDTA complex.
4. A solution as claimed in claim 3 , in which the EDTA complex is produced from at least one compound selected from the group consisting of sodium EDTA and potassium EDTA.
5. A solution as claimed in claim 1 , which comprises chlorocresol as preservative.
6. The injectable trace element solution of claim 1 , wherein the selenium is present in an amount of 5 mg/ml.
7. The injectable trace element solution of claim 1 , further comprising 5-10 mg/ml chromium.
8. A trace element solution, which comprises:
(a) 35-50 mg/ml zinc;
(b) 10-15 mg/ml manganese;
(c) 5-10 mg/ml selenium; and
(d) iron,
wherein a total concentration of zinc, manganese, selenium and iron in the solution is at least 60 mg/ml.
9. A solution as claimed in claim 8 , further comprising 5-10 mg/ml chromium.
10. A solution as claimed in claim 8 , wherein the iron in solution is 5-50 mg/ml.
11. A solution as claimed in claim 8 , further comprising 20-400 mg/ml iodine.
12. The trace element solution of claim 10 , further comprising 20-400 mg/ml iodine.