Methods and materials for treating cancer
This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.
1. A composition comprising nucleic acid encoding an HIF-2α antigen, a SOX-10 antigen, and a C-MYC antigen, wherein said composition comprises less than 100 separate nucleic acid molecules.
2. The composition of claim 1 , wherein said composition comprises a nucleic acid molecule encoding said HIF-2α antigen, a nucleic acid molecule encoding said SOX-10 antigen, and a nucleic acid molecule encoding said C-MYC antigen.