Mitral valve anchoring
Disclosed herein are prosthetic devices and related methods for implantation at the native mitral valve of the heart by drawing an atrial portion and a ventricular portion toward each other from opposite sides of the native mitral valve, clamping the native mitral valve therebetween. One or more retention members passing through the mitral valve orifice or through a puncture in the native valve anatomy can couple the atrial and ventricular members together and keep them anchored onto the native mitral valve anatomy. The atrial portion can seat against the atrial side of the mitral annulus while the ventricular portion can include hooks and/or a sub-annular ring that engage and capture the native mitral valve apparatus to provide anchorage. The described technology can avoid the need to use sutures to anchor a prosthetic device at the mitral valve region.
1. A prosthetic mitral valve comprising:
an atrial portion for placement in the left atrium;
a ventricular portion for placement in the left ventricle; and
one or more retention members that couple the atrial portion to the ventricular portion;
wherein the atrial portion includes a prosthetic valve structure;
wherein the ventricular portion is configured to be implanted under the native mitral valve annulus and behind the native mitral valve leaflets with the native mitral chordae tendineae intact;
wherein the atrial portion and the ventricular portion are configured to become engaged on opposite sides of the native mitral valve annulus via the one or more retention members to anchor the prosthetic mitral valve at the native mitral valve region;
wherein the one or more retention members include a spring-biasing mechanism; and
wherein the one or more retention members are mounted in the atrial portion such that a user can depress the retention members relative to the atrial portion, rotate the retention members to position a hook under the ventricular portion, and then release the retention members to allow the spring-biasing mechanism to cause the hook to engage the ventricular portion.
2. The prosthetic mitral valve of claim 1 , wherein a length of the one or more retention members between the atrial portion and the ventricular portion is configured to shorten, thereby reducing a distance between the atrial portion and the ventricular portion.
3. The prosthetic mitral valve of claim 1 , wherein the ventricular portion comprises a single ventricular member having a substantially annular shape and configured to be implanted under a majority of the circumference of the native mitral valve annulus.
4. The prosthetic mitral valve of claim 3 , wherein the single ventricular portion member comprises a ring with a break at one location around a perimeter of the ring, the break being sized to allow a free edge of a native mitral valve leaflet to enter into the ring through the break.
5. The prosthetic mitral valve of claim 4 , wherein the atrial portion includes a protrusion configured to be received by the break in the perimeter of the ventricular member for sealing the break.
6. The prosthetic mitral valve of claim 1 , wherein the one or more retention members are mounted in the atrial portion such that the one or more retention members can be actuated by a user when the atrial portion and ventricular portion are brought together.