Arrangement for facilitating wound healing, a method for measuring wound healing and a wound dressing
The present invention relates to the field of electrotherapy and measuring by means of electric cur-rents for diagnostic purposes, and more particularly to an electrode arrangement for facilitating wound healing, a method for measuring wound healing and a wound dressing having an electrode arrangement. A wound dressing according is described which includes at least two impedance reference electrodes, a frame like counter-electrode and stimulation electrodes in a form of an array; and a bioadhesive affinity layer surrounding the stimulation electrodes; said wound dressing being suited for applying on top of the wound so that the stimulation electrode array is on the wound area, and that the at least two impedance reference electrodes and the frame like counter-electrode are suited for placing in contact with the healthy skin surrounding the wound area; which electrodes, are suited for applying LIDC type electrical stimulation current to the wound area and for bioimpedance measurement.
1. A wound dressing comprising:
stimulation electrodes arranged in an array, said array of stimulation electrodes capable of providing low intensity direct current (LIDC) type electrical stimulation current to a wound area,
at least two impedance reference electrodes arranged outside said array of stimulation electrodes, and
at least one frame-like counter-electrode arranged outside said array of stimulation electrodes,
wherein the frame-like counter-electrode extends contiguously in a parallel direction to the stimulation electrodes at adjacent sides of the stimulation electrode array.
2. The wound dressing according to claim 1 , wherein the stimulation electrodes, impedance reference electrodes and at least one frame-like counter electrode are arranged on a printed substrate.
3. The wound dressing according to claim 1 , further comprising at least two frame-like counter electrodes, wherein at least one of the frame like counter electrodes forms a corner around the array of stimulation electrodes.
4. The wound dressing according to claim 1 , further comprising a bioadhesive affinity layer surrounding the stimulation electrodes.
5. The wound dressing according to claim 2 , wherein said wound dressing is capable of being applied on top of a wound so that the stimulation electrode array can be on a wound area while the at least two impedance reference electrodes and the frame-like counter-electrode can be placed in contact with healthy skin surrounding the wound area.
6. The wound dressing according to claim 1 , wherein the stimulation electrodes and frame-like counter-electrode(s) are capable of bioimpedance measurement with measurement frequencies in the range of 10 Hz-200 000 Hz.
7. The wound dressing according to claim 1 , wherein a polarity of the frame-like counter-electrode(s) and the stimulation electrodes is switchable.
8. The wound dressing according to claim 1 , further comprising a button battery, a printed battery structure or an electrochemical cell used as a power source for the stimulation electrodes and frame-like counter-electrode(s).
9. The wound dressing according to claim 1 , further comprising a tether with the electrical connections of the stimulation electrodes and frame-like counter-electrode(s).
10. The wound dressing according to claim 4 , wherein the bioadhesive affinity layer includes a peptide modified polysaccharide bioadhesive having a peptide component and a polysaccharide component.
11. The wound dressing according to claim 1 , further comprising a bioactive layer containing a biopolymer based bioactive glass granules or spheres containing screen printable paste.
12. The wound dressing according to claim 1 , wherein the stimulation electrodes and frame-like counter-electrode(s) are multiplexed.
13. A method for measuring wound healing when providing low intensity direct current (LIDC) type electrical stimulation current to a wound area with the aid of stimulation electrodes in a form of an array, said method comprising the steps of:
performing bioimpedance measurement with at least one frame-like counter-electrode arranged outside an array of stimulation electrodes and with said array of stimulation electrodes;
wherein said stimulation electrodes and frame-like counter-electrode(s) are complemented with at least two impedance reference electrodes arranged outside said array of stimulation electrodes and arranged suitably for placing in contact with healthy skin surrounding a wound area, and
wherein the frame-like counter-electrode extends contiguously in a parallel direction to the stimulation electrodes at adjacent sides of the stimulation electrode array.
14. The method according to claim 13 , wherein the stimulation electrodes and frame-like counter-electrode(s) are suited for bioimpedance measurement with measurement frequencies in the range of 10 Hz-200 000 Hz.