IP Library › Granted Patent US 10,238,787
Granted Patent B2
US 10,238,787 · App. 15/024,570 · Granted Mar 26, 2019

Blood component separation device

Inventors: Hiroaki Takuwa (Hiroshima, JP); Satoshi Hirai (Hiroshima, JP); Yoshiki Tanaka (Hiroshima, JP); Shuji Nakamura (Gunma, JP); Katsuyuki Sado (Gunma, JP); Kenta Kaneda (Gunma, JP)
Assignee: TRANSELL Co., Ltd.
A61M1/3693A61J1/1418A61J1/1475A61J1/2003A61J1/22A61M1/029A61J1/067A61M2202/0415A61M2202/0429
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Quick Facts
Patent No.
US 10,238,787
App. No.
15/024,570
Granted
Mar 26, 2019
Kind
B2
Abstract

A blood reservoir ( 20 ) for storing blood includes a first storage section ( 21 ), a second storage section ( 22 ), and a third storage section ( 23 ) that is provided between the first storage section and the second storage section, and communicates with the first storage section and the second storage section. A volume of the blood reservoir ( 20 ) can be adjusted by changing the amount of expansion or contraction of a bellows structure ( 28 ) using a bellows adjustment mechanism ( 83, 93 ).

Claims (49)

1. A blood component separation device, comprising:

a blood reservoir configured to store blood and used for centrifugation of blood stored in the blood reservoir, wherein the blood reservoir comprises:

a first storage section, a second storage section, and a third storage section that is provided between the first storage section and the second storage section, and communicates with the first storage section and the second storage section,

a support member configured to prevent deformation of the third storage section during centrifugation;

a bottom cap that is in contact with at least a part of a bottom of the first storage section, wherein one of the support member and the bottom cap has a male thread and the other of the support member and the bottom cap has a female thread;

a bellows structure provided on the blood reservoir, configured to be expandable and contractable; and

a bellows adjustment mechanism comprising the male thread and the female thread, and configured to adjust an amount of expansion or contraction of the bellows structure based on a depth of screwing the male thread into the female thread, which adjusts the amount of expansion or contraction of the bellows structure,

wherein a volume of the blood reservoir is adjusted by adjusting the bellows structure using the bellows adjustment mechanism.

2. The blood component separation device according to claim 1 , wherein the bellows structure is provided on the first storage section that stores red blood cell components after centrifugation.

3. The blood component separation device according to claim 1 , wherein the blood reservoir is integrally formed as a single piece, including the bellows structure.

4. The blood component separation device according to claim 1 , wherein the bottom cap has a scale that serves as an indicator for adjusting the amount of expansion or contraction of the bellows structure.

5. The blood component separation device according to claim 1 , wherein the device is configured so that a communication between the first storage section and the third storage section can be blocked, and a communication between the second storage section and the third storage section can be blocked.

6. The blood component separation device according to claim 1 , further comprising a flow path through which blood components in the third storage section flow out of the blood reservoir.

7. The blood component separation device according to claim 1 , comprising a first blocking member and a second blocking member in the blood reservoir,

wherein the first blocking member is configured to be able to block the communication between the first storage section and the third storage section, and

the second blocking member is configured to be able to block the communication between the second storage section and the third storage section.

8. The blood component separation device according to claim 7 , wherein the first blocking member moves in the first storage section to block the communication between the first storage section and the third storage section.

9. The blood component separation device according to claim 8 , comprising a first rod that holds the first blocking member and is drawn out of the blood reservoir,

wherein the first rod is moved to allow the first blocking member to move.

10. The blood component separation device according to claim 9 , comprising a first flow path that provides a communication between the third storage section and the outside of the blood reservoir while the first blocking member blocks the communication between the first storage section and the third storage section, and the second blocking member blocks the communication between the second storage section and the third storage section.

11. The blood component separation device according to claim 10 , further comprising a second flow path that provides a communication between the third storage section and the outside of the blood reservoir while the first blocking member blocks the communication between the first storage section and the third storage section, and the second blocking member blocks the communication between the second storage section and the third storage section.

12. The blood component separation device according to claim 11 , wherein at least one of the first flow path and the second flow path is provided in the first rod.

13. The blood component separation device according to claim 7 , wherein the second blocking member moves in the second storage section to block the communication between the second storage section and the third storage section.

14. The blood component separation device according to claim 13 , comprising a second rod that holds the second blocking member and is drawn out of the blood reservoir,

wherein the second rod is moved to allow the second blocking member to move.

15. The blood component separation device according to claim 13 , further comprising a movement restriction mechanism that restricts a movement of the second blocking member so as to prevent the second blocking member from moving in the blood reservoir and blocking the communication between the second storage section and the third storage section during centrifugation.

16. The blood component separation device according to claim 7 , further comprising a pressure release mechanism that releases pressure in the third storage section when the first blocking member blocks the communication between the first storage section and the third storage section, and the second blocking member blocks the communication between the second storage section and the third storage section.

17. The blood component separation device according to claim 16 , wherein the pressure release mechanism includes a through hole formed in the second blocking member so as to provide a communication between the second storage section and the third storage section.

18. The blood component separation device according to claim 17 , wherein the pressure release mechanism further includes a one-way valve provided in the through hole, and

the one-way valve allows a flow from the third storage section to the second storage section through the through hole, and prevents a flow from the second storage section to the third storage section through the through hole.

19. The blood component separation device according to claim 17 , wherein the pressure release mechanism further includes a tube, one end of which is connected to the through hole, and

the other end of the tube is open in a position above a blood surface in the blood reservoir.

20. The blood component separation device according to claim 16 , wherein the pressure release mechanism forms a flow path for introducing outside air into the third storage section when white blood cell components in the third storage section are aspirated and collected while the first blocking member blocks the communication between the first storage section and the third storage section, and the second blocking member blocks the communication between the second storage section and the third storage section.

21. A blood component separation device, comprising:

a blood reservoir configured to store blood and used for centrifugation of blood stored in the blood reservoir, wherein the blood reservoir comprises:

a first storage section, a second storage section, and a third storage section that is provided between the first storage section and the second storage section, and communicates with the first storage section and the second storage section; and

a flow path through which blood components in the third storage section flow out of the blood reservoir;

a bellows structure provided on the blood reservoir, configured to be expandable and contractable; and

a bellows adjustment mechanism comprising a male thread and a female thread, and configured to adjust an amount of expansion or contraction of the bellows structure based on a depth of screwing the male thread into the female thread, which adjusts the amount of expansion or contraction of the bellows structure,

wherein a volume of the blood reservoir is adjusted by adjusting the amount of expansion or contraction of the bellows structure.

22. A blood component separation device, comprising:

a blood reservoir for storing blood and is used for centrifugation of blood stored in the blood reservoir, wherein the blood reservoir comprises:

a first storage section, a second storage section, and a third storage section that is provided between the first storage section and the second storage section, and communicates with the first storage section and the second storage section, and

a first blocking member and a second blocking member in the blood reservoir,

wherein the first blocking member is configured to block communication between the first storage section and the third storage section,

the second blocking member is configured to block communication between the second storage section and the third storage section;

a bellows structure provided on the blood reservoir, configured to be expandable and contractable; and

a bellows adjustment mechanism comprising a male thread and a female thread, and configured to adjust an amount of expansion or contraction of the bellows structure based on a depth of screwing the male thread into the female thread, which adjusts the amount of expansion or contraction of the bellows structure,

wherein a volume of the blood reservoir is adjusted by adjusting the amount of expansion or contraction of the bellows structure.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: JMS CO., LTD.; JIMRO CO., LTD.
To: TRANSELL CO., LTD.
Reel/Frame 048209/0492 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 24, 2016
From: TAKUWA, HIROAKI; HIRAI, SATOSHI; TANAKA, YOSHIKI; NAKAMURA, SHUJI; SADO, KATSUYUKI; KANEDA, KENTA
To: JMS CO., LTD.; JIMRO CO., LTD.
Reel/Frame 038243/0476 →
Priority Claims (1)
JP 2013-198558 · Sep 25, 2013 · national
Continuity (1)
Related Publication 20160235906A1 · Aug 18, 2016
Cited By (4)
US 12,214,366 US 12,257,378 US 12,345,352 US 12,478,712