IP Library › Granted Patent US 10,245,283
Granted Patent B2
US 10,245,283 · App. 15/830,307 · Granted Apr 2, 2019

Compositions and methods to affect skin irritation

Inventors: Ronald E. Utecht (Volga, SD); Therese M. Downey (Sioux Falls, SD); Miri Seiberg (Princeton, NJ); Stanley S. Shapiro (Roseland, NJ); Jack V. Foster, Jr. (New Orleans, LA)
Assignees: ALUMEND, LLC; WAVEPHARMA, LLC
A61K31/737A61F13/8405A61K8/347A61K8/671A61K8/736A61K9/0014A61K31/05A61K31/07A61K31/185A61K31/203A61K31/722A61K45/06A61Q19/08A61K2800/75A61K2800/782
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Quick Facts
Patent No.
US 10,245,283
App. No.
15/830,307
Granted
Apr 2, 2019
Kind
B2
Abstract

Compositions are described that contain treated chitosan, modified chitosan and/or modified and treated chitosan for use in formulations for skin, hair and nails, and in compositions and methods of reducing topical agent-induced skin irritation and inflammation.

Claims (3)

1. A sunscreen composition comprising: (a) at least one sunscreen agent that causes skin irritation and/or skin inflammation and/or IL-1α secretion, and (b) at least one chitosan covalently modified with an octane sulfonic acid via a sulfonamide linkage, wherein the composition provides a reduction in skin irritation and/or a reduction in skin inflammation and/or a reduction in irritant-induced IL-1α secretion after contact with the composition compared with a control composition comprising the sunscreen agent but not the chitosan.

2. The composition of claim 1 , wherein the at least one covalently modified chitosan comprises about 0.0001-5% W/V of the total weight of the composition.

3. The composition of claim 1 , which is in the form of a solution, suspension, emulsion, lotion, cream, gel, or spray.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2025
From: DOWNEY, THERESE M.; UTECHT, RONALD E.
To: ALUMEND, LLC
Reel/Frame 070401/0977 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2025
From: SEIBERG, MIRI; SHAPIRO, STANLEY S.; FOSTER, JR., JACK V.
To: WAVEPHARMA, LLC
Reel/Frame 070402/0306 →
Continuity (3)
Continuation 15387138 · Dec 21, 2016
Provisional Application 62271591 · Dec 28, 2015
Related Publication 20180092940A1 · Apr 5, 2018