Oral care composition containing zinc salts and calcium carbonate

Inventors: Ravi Subramanyam (Belle Mead, NJ); Suzanne Jogun (Wayne, NJ); Mahmoud Hassan (Somerset, NJ); Navin Lewis (Mumbai, IN); Xiao Yi Huang (Guangzhou, CN); Shao Peng Xu (Guangzhou, CN)

Assignee: Colgate-Palmolive Company

A61K8/27 A61K8/0237 A61K8/042 A61K8/19 A61K8/21 A61K8/25 A61K8/365 A61K8/37 A61Q11/00

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Quick Facts

Patent No.: US 10,251,823
App. No.: 15/525,381
Granted: Apr 9, 2019
Kind: B2

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Abstract

The present invention provides an oral care composition comprising: (a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and (b) a second composition comprising a calcium carbonate abrasive; wherein the first composition and/or the second composition further comprises a second zinc compound selected from zinc oxide, zinc carbonate and zinc tartrate; and wherein the oral care composition optionally further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.

Claims (25)

1. An oral care composition comprising:

(a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and

(b) a second composition comprising a calcium carbonate abrasive; wherein the second composition further comprises a second zinc compound and wherein the second zinc compound is zinc oxide.

2. The oral care composition of claim 1 , wherein the oral care composition further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.

3. The oral care composition of claim 1 , wherein the concentration of the first zinc compound in the oral care composition is from 0.25 to 0.75 weight % based on the total weight of the oral care composition.

4. The oral care composition of claim 1 , wherein the concentration of the second zinc compound in the oral care composition is from 0.5 to 1.5 weight %, based on the total weight of the oral care composition.

5. The oral care composition of claim 1 , wherein the weight ratio of the second zinc compound to the first zinc compound in the oral care composition is from 1.5:1 to 4.5:1.

6. The oral care composition of claim 1 , wherein the first zinc compound is zinc citrate.

7. The oral care composition of claim 1 , wherein the concentration of the silica abrasive in the oral care composition is from 1 to 10 weight %, based on the total weight of the composition.

8. The oral care composition of claim 1 , wherein the concentration of the calcium carbonate abrasive in the oral care composition is from 20 to 40 weight %, based on the total weight of the composition.

9. The oral care composition of claim 1 wherein the first composition is a toothpaste.

10. The oral care composition of claim 1 wherein the first composition is a gel.

11. The oral care composition of claim 1 wherein the second composition is a toothpaste.

12. The oral care composition of claim 1 , wherein the weight ratio of the first composition to the second composition is from 1:8 to 1:1.

13. The oral care composition of claim 1 , wherein the oral care composition is a striped dentifrice comprising a main dentifrice material and a stripe dentifrice material, the first composition being the stripe dentifrice material and the second composition being the main dentifrice material.

14. The oral care composition of claim 2 , wherein the tartar control agent is a monobasic, dibasic or tribasic sodium phosphate; a mono-, di- or trisodium pyrophosphate; a mono-, di- or tripotassium pyrophosphate; tetrasodium pyrophosphate (TSPP); tetrapotassitim pyrophosphate (TKPP); sodium or potassium tripolyphosphate; sodium or potassium tetrapoiyphosphate; sodium or potassium trimetaphosphate; sodium or potassium hexametaphosphate; or a combination of any two or more thereof.

15. The oral care composition according to claim 1 , wherein the composition comprises a fluoride source.

16. The oral care composition according to claim 15 , wherein the fluoride source is at least one selected from stannous fluoride, sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, and ammonium fluoride.

17. A method of reducing or inhibiting biofilm formation in an oral cavity, the method comprising contacting the oral cavity with an oral care composition according to claim 1 .

18. A method of enhancing the antibacterial efficacy of an oral care composition comprising a calcium carbonate abrasive and at least one zinc salt, the method comprising providing the oral care composition according to claim 1 as an oral care composition.

19. A method of forming an oral care composition, comprising adding

(b) a second composition comprising a calcium carbonate abrasive;

wherein the second composition further comprises a second zinc compound and wherein the second zinc compound is zinc oxide;

and wherein the concentration of the first zinc compound in the second composition is less than 0.01 weight %, based on the weight of the second composition.

Priority Claims (1)

IN 3300/DEL/2014 · Nov 14, 2014 · national

Continuity (1)

Related Publication 20170333310A1 · Nov 23, 2017