IP Library › Granted Patent US 10,251,894
Granted Patent B2
US 10,251,894 · App. 15/917,245 · Granted Apr 9, 2019

Anticonvulsant activity of steroids

Inventors: Michael A. Rogawski (Sacramento, CA); Dorota Zolkowska (Davis, CA)
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
A61K31/57A61K9/0019A61K9/08A61K31/56A61K31/573A61K47/40
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Quick Facts
Patent No.
US 10,251,894
App. No.
15/917,245
Granted
Apr 9, 2019
Kind
B2
Abstract

The present invention relates to methods of preventing, inhibiting, delaying, and/or mitigating seizures by administration of a steroid, e.g., a neurosteroid, e.g., allopregnanolone.

Claims (3)

1. A method of treating post-partum depression in a subject in need thereof, comprising administering to the subject an effective amount of a composition comprising allopregnanolone and sulfobutylether-beta-cyclodextrin salt, wherein the composition is administered intravenously (i.v.).

2. The method of claim 1 , wherein the subject is a human.

3. The method of claim 1 , wherein the composition further comprises a buffer.

Continuity (4)
Division 15632360 · Jun 25, 2017
Continuation 14646886
Provisional Application 61732252 · Nov 30, 2012
Related Publication 20180193357A1 · Jul 12, 2018
Cited By (9)
US 12,186,327 US 12,201,640 US 12,358,942 US 12,370,200 US 12,409,185 US 12,473,327 US 12,534,495 US 12,655,175 US 12,714,717