Pharmaceutical composition and method of treating a microbial infection with sulcotidil
The present invention relates to the use of one or more compounds selected from the following classes of biologically active agents: an a-adrenergic antagonist, an anthelmintic agent, an antifungal agent, an antimalarial agent, an antineoplastic agent, an antipsychotic agent, an antioxidant, a vasodilator and/or a vitamin, or a pharmaceutically acceptable derivative thereof, for use in the treatment of a microbial infection and in particular for killing multiplying, non-multiplying and/or clinically latent microorganisms associated with such an infection.
1. A method of killing multiplying, non-multiplying and/or clinically latent microorganisms associated with a bacterial infection which comprises administering to a mammal, including man, suloctidil, or a pharmaceutically acceptable salt thereof.
2. A method of killing multiplying, non-multiplying and/or clinically latent microorganisms associated with a bacterial infection which comprises administering to a mammal, including man, suloctidil, or a pharmaceutically acceptable salt thereof wherein the infection is caused by Staphylococcus aureus , or Escherichia coli.
3. The method according to claim 1 , wherein the infection is caused by Staphylococcus aureus or Escherichia coli.
4. The method according to claim 1 , wherein suloctidil is administered.
5. The method according to claim 2 , wherein suloctidil is administered.
6. The method according to claim 4 or claim 5 wherein the infection is caused by S. aureus.
7. The method according to claim 1 or claim 2 , wherein the infection is caused by Escherichia coli.
8. The method according to claim 6 , wherein the infection is caused by MSSA and/or MRSA.