IP Library › Granted Patent US 10,272,086
Granted Patent B2
US 10,272,086 · App. 14/783,544 · Granted Apr 30, 2019

Minoxidil for suppressing androgen receptor function

Inventor: Cheng-Lung Hsu (Gueishan Township, Taoyuan County, TW)
Assignees: Chang Gung Memorial Hospital, Linkou; Wilson Hsu
A61K31/506A61K31/07A61K31/203A61K31/65A61K45/06
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Quick Facts
Patent No.
US 10,272,086
App. No.
14/783,544
Granted
Apr 30, 2019
Kind
B2
Abstract

Methods for treating androgen receptor related diseases and suppressing androgen receptor related function by administering an effective amount of minoxidil are provided. Methods for treating or prophylactically treating acne by administering an effective amount of minoxidil are also provided. An anti-acne medication is optionally administered to treat or prophylactically treat acne.

Claims (13)

1. A method for treating acne, consisting of administering an effective amount of minoxidil or a pharmaceutically acceptable salt thereof to a subject in need thereof.

2. The method of claim 1 , wherein the effective amount of minoxidil is about 5 mg to about 100 mg per day.

3. A method for treating acne, consisting of administering an effective amount of minoxidil or a pharmaceutically acceptable salt thereof and an anti-acne medication selected from the group consisting of vitamin A, antibiotic, oral contraceptive, and retinoid to a subject in need thereof, wherein the erythema or swelling of acne is reduced.

4. The method of claim 3 , wherein said administering is topical administration.

5. The method of claim 4 , wherein the topical administration is once a day to three times a day.

6. The method of claim 3 , wherein the anti-acne medication is vitamin A.

7. The method of claim 3 , wherein the anti-acne medication is one or more antibiotics.

8. The method of claim 7 , wherein the antibiotic is tetracycline or a derivative thereof.

9. The method of claim 7 , wherein the antibiotic is minocycline or a derivative thereof.

10. The method of claim 7 , wherein the antibiotic is doxycycline or a derivative thereof.

11. The method of claim 3 , wherein the anti-acne medication is an oral contraceptive.

12. The method of claim 3 , wherein the anti-acne medication is a retinoid.

13. The method of claim 12 , wherein the retinoid is isoretinoin.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 24, 2026
From: CHANG GUNG MEMORIAL HOSPITAL, LINKOU; HSU, WILSON
To: PANION & BF BIOTECH INC.
Reel/Frame 073869/0900 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2015
From: HSU, CHENG-LUNG, DR
To: CHANG GUNG MEMORIAL HOSPITAL, LINKOU
Reel/Frame 036875/0471 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2015
From: HSU, CHENG-LUNG, DR
To: HSU, WILSON, MR
Reel/Frame 036875/0474 →
Continuity (2)
Provisional Application 61817830 · Apr 30, 2013
Related Publication 20160045499A1 · Feb 18, 2016
Cited By (1)
US 12,491,184