Toll like receptor modulator compounds
The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D] pyrimidine compounds and pharmaceutical compositions which, among other things, modulate toll-like receptors (e.g. TLR-8), and methods of making and using them.
1. A method of treating a hepatitis B viral infection, comprising administering to an individual in need thereof a therapeutically effective amount of a compound which is
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , further comprising administering one or more additional therapeutic agents.
3. The method of claim 1 , further comprising administering tenofovir alafenamide, tenofovir alafenamide fumarate, or tenofovir alafenamide hemifumarate.
4. A method of treating a hepatitis B viral infection, comprising administering to an individual in need thereof a therapeutically effective amount of a compound which is
5. The method of claim 4 , further comprising administering one or more additional therapeutic agents.
6. The method of claim 4 , further comprising administering tenofovir alafenamide, tenofovir alafenamide fumarate, or tenofovir alafenamide hemifumarate.