IP Library Granted Patent US 10,293,019
Granted Patent B2
US 10,293,019 · App. 15/536,952 · Granted May 21, 2019

Pharmaceutical composition for treatment of or remission in elderly or terminal cancer patient

Inventor: Hiromi Wada (Kyoto, JP)
Assignee: DELTA-FLY PHARMA, INC.
A61K38/05A61K38/55A61K45/00A61K45/06A61P35/04
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Quick Facts
Patent No.
US 10,293,019
App. No.
15/536,952
Granted
May 21, 2019
Kind
B2
Abstract

An object of the present invention is to provide a novel treatment method with fewer side effects for elderly cancer patients and terminal cancer patients. A pharmaceutical composition for treating or putting an elderly or a terminal cancer patient into remission, comprising, as an active ingredient, (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoylamino]-4-methylpentanoic acid or a pharmacologically acceptable salt thereof.

Claims (4)

1. A method for treating or putting into remission a patient in need thereof, said method comprising:

selecting a solid cancer patient aged 70 or more or a terminal solid cancer patient, the patient's neutrophil count to lymphocyte count ratio in peripheral blood being 4 or more or the patient's platelet count to lymphocyte count ratio being 1.5 or more, wherein the peripheral blood of said cancer patient has a normal range of platelet counts or a normal range of neutrophil counts; and

administering to said patient a composition comprising, as an active ingredient, sufficient (2S)-2- [(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoylamino]-4-methylpentanoic acid or a pharmacologically acceptable salt thereof to provide said patient with a dosage 10 mg/body/day.

2. The method of claim 1 , which additionally comprises administering to said patient a sufficient amount of an anticancer agent or a molecular targeted drug to provide said patient with a dosage in the range from 0.0001 mg to 1000 mg/body/day.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2017
From: WADA, HIROMI
To: DELTA-FLY PHARMA, INC.
Reel/Frame 042747/0862 →
Priority Claims (1)
JP 2014-255403 · Dec 17, 2014 · national
Continuity (1)
Related Publication 20180256668A1 · Sep 13, 2018