IP Library Granted Patent US 10,308,642
Granted Patent B2
US 10,308,642 · App. 15/765,011 · Granted Jun 4, 2019

Anti-hepatitis B virus agent

Inventors: Kazuki Shimane (Toyama, JP); Yasuhito Tanaka (Nagoya, JP)
Assignees: FUJIFILM Toyama Chemical Co., Ltd.; PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
C07D409/04A61K31/443A61K31/4422A61K31/4436A61K31/4439A61P31/20C07D213/80C07D405/10C07D409/10
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Quick Facts
Patent No.
US 10,308,642
App. No.
15/765,011
Granted
Jun 4, 2019
Kind
B2
Abstract

An anti-hepatitis B virus agent comprising a compound represented by general formula [1], wherein R 1 represents an aryl group, which may be substituted, or the like; R 2 represents an aryl group, which may be substituted, or the like; and R 3 represents a hydrogen atom or the like; or a salt thereof.

Claims (12)

1. A method of treating hepatitis B virus, the method comprising administering an anti-hepatitis B virus agent to a patient in need thereof, the anti-hepatitis B virus agent comprising a compound represented by general formula [1]:

wherein R 1 represents an aryl group which may be substituted or a heterocyclic group which may be substituted;

R 2 represents a C 3-8 cycloalkyl group which may be substituted, an aryl group which may be substituted, or a heterocyclic group which may be substituted; and

R 3 represents a hydrogen atom or a carboxyl protecting group, or a salt thereof.

2. The method according to claim 1 , wherein R 1 represents an aryl group which may be substituted.

3. The method according to claim 1 , wherein R 1 represents a phenyl group which may be substituted.

4. The method according to claim 1 , wherein R 1 represents a heterocyclic group which may be substituted.

5. The method according to claim 1 , wherein R 1 represents a bicyclic heterocyclic group which may be substituted.

6. The method according to claim 1 , wherein R 2 represents an aryl group which may be substituted.

7. The method according to claim 1 , wherein R 2 represents a phenyl group which may be substituted.

8. The method according to claim 1 , wherein R 2 represents a heterocyclic group which may be substituted.

9. The method according to claim 1 , wherein R 2 represents a monocyclic heterocyclic group which may be substituted.

Assignments (2)
MERGER AND CHANGE OF NAME Recorded Mar 5, 2019
From: TOYAMA CHEMICAL CO., LTD.; FUJIFILM TOYAMA CHEMICAL CO., LTD.
To: FUJIFILM TOYAMA CHEMICAL CO., LTD.
Reel/Frame 048499/0779 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2018
From: SHIMANE, KAZUKI; TANAKA, YASUHITO
To: TOYAMA CHEMICAL CO., LTD.; PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
Reel/Frame 045397/0483 →
Priority Claims (1)
JP 2015-197725 · Oct 5, 2015 · national
Continuity (1)
Related Publication 20180291011A1 · Oct 11, 2018