IP Library › Granted Patent US 10,327,650
Granted Patent B2
US 10,327,650 · App. 14/462,418 · Granted Jun 25, 2019

Devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in cardio-pulmonary resuscitation (CPR) process

Inventors: Jun Xu (Beijing, CN); Xuezhong Yu (Beijing, CN); Fei Han (Shenzhen, CN); Liangliang Zheng (Beijing, CN); Cheng Wang (Shenzhen, CN); Xiaocui Zhang (Shenzhen, CN); Chen Li (Beijing, CN); Jingming Yang (Shenzhen, CN); Xingliang Jin (Shenzhen, CN); Yangyang Fu (Beijing, CN); Dongqi Yao (Beijing, CN)
Assignees: PEKING UNION MEDICAL COLLEGE HOSPITAL; SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
A61B5/024A61B5/026A61B5/02416A61B5/14551A61B5/7235A61B5/7282A61H31/00A61H31/005A61B2505/01A61H2230/04A61H2230/207
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Quick Facts
Patent No.
US 10,327,650
App. No.
14/462,418
Granted
Jun 25, 2019
Kind
B2
Abstract

This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Claims (35)

1. A device for real-time recognition of restoration of spontaneous circulation (ROSC) in a cardio-pulmonary resuscitation (CPR) process, comprising:

a signal acquisition apparatus comprising a sensor for blood oxygen saturation

detection based upon light absorption and acquiring pulse oximetry waveform signals of a patient, at least one pulse oximetry waveform comprising a manual compression waveform signal and a spontaneous circulation waveform signal; and

a signal analysis apparatus comprising a frequency-domain recognition logic for analyzing the pulse oximetry waveform signals in a frequency domain to identify a first frequency and a first amplitude for the manual compression waveform signal and a second frequency and a second amplitude for the spontaneous circulation waveform signal to determine whether there is ROSC in the CPR process by detecting time-varying features of spectral peaks of the signals including the second frequency and the second amplitude of the spontaneous circulation waveform signal in the frequency domain.

2. The device of claim 1 , wherein: the signal analysis apparatus further comprises time-domain recognition logic, said time-domain recognition logic provided for determining whether there is ROSC in the CPR process by detecting a time envelope of the signals in the time domain.

3. The device of claim 2 , wherein: the time-domain recognition logic determines that there is ROSC when continuous and regular envelope features are recognized.

4. The device of claim 1 , wherein: the frequency-domain recognition logic determines that there is ROSC when spectral peaks are recognized continuously at different frequencies or significant amplitude change is recognized for spectral peaks within a certain period.

5. A restoration of spontaneous circulation (ROSC) recognition and post-ROSC circulation quality evaluation system, comprising:

an ROSC recognition device and a post-ROSC circulation quality evaluation apparatus for evaluating post-ROSC circulation quality;

the ROSC recognition device comprises:

a signal acquisition apparatus comprising a sensor for blood oxygen saturation

detection based upon light absorption and acquiring pulse oximetry waveform signals of a patient, at least one pulse oximetry waveform comprising a manual compression waveform signal and a spontaneous circulation waveform signal; and

a signal analysis apparatus comprising a frequency-domain recognition logic for analyzing the pulse oximetry waveform signals in a frequency domain to identify a first frequency and a first amplitude for the manual compression waveform signal and a second frequency and a second amplitude for the spontaneous circulation waveform signal to determine whether there is ROSC in the CPR by detecting time-varying features of spectral peaks of the signals including the second frequency and the second amplitude of the spontaneous circulation waveform signal in the frequency domain.

6. The ROSC recognition and post-ROSC circulation quality evaluation system of claim 5 , wherein the post-ROSC circulation quality evaluation apparatus evaluates the post-ROSC circulation quality based on variations of cardiac stroke volume within a certain period or based on variations of pulse rate.

7. The ROSC recognition and post-ROSC circulation quality evaluation system of claim 6 , wherein after the ROSC recognition device has determined there is ROSC, the post-ROSC circulation quality evaluation apparatus calculates area characteristics of AC components of pulse signals sampled by the ROSC recognition device to evaluate the stroke volume variations under spontaneous cardiac rhythm to reflect post-ROSC circulation quality.

8. A restoration of spontaneous circulation (ROSC) feedback system in a cardio-pulmonary resuscitation (CPR) process, comprising:

an ROSC recognition and post-ROSC circulation quality evaluation apparatus configured to recognize ROSC in the CPR process in real time from pulse oximetry waveform signals derived from a pulse oximeter, and to evaluate post-ROSC circulation quality, at least one pulse oximetry waveform signal comprising a manual compression waveform signal and a spontaneous circulation waveform signal, said apparatus being further configured to evaluate stability of the post-ROSC circulation quality, wherein the ROSC recognition and post-ROSC circulation quality evaluation apparatus comprises a frequency-domain recognition logic provided for analyzing the pulse oximetry waveform signals in a frequency domain to identify a first frequency and a first amplitude for the manual compression waveform signal and a second frequency and a second amplitude for the spontaneous circulation waveform signal to determine whether there is ROSC in the CPR process by detecting time-varying features of spectral peaks of the sampled signals including the second frequency and the second amplitude of the spontaneous circulation waveform signal in the frequency domain; and

a CPR apparatus for providing compression output to a patient;

wherein, upon detection of the ROSC, the ROSC recognition and post-ROSC circulation quality evaluation apparatus controls the CPR apparatus to stop compression output and start the post-ROSC circulation quality evaluation;

wherein, when the post-ROSC circulation quality is evaluated to be unstable, the ROSC recognition and post-ROSC circulation quality evaluation apparatus controls the CPR apparatus to restart the compression output, and restarts the real-time recognition of ROSC.

9. The ROSC feedback system of claim 8 , further comprising:

a CPR quality evaluation apparatus for evaluating CPR quality;

wherein, while the CPR apparatus is providing the compression output, the CPR apparatus interacts with the CPR quality evaluation apparatus so that the CPR quality evaluation apparatus recognizes CPR compression state and provides feedback to the CPR apparatus to achieve an optimal compression output.

10. The ROSC feedback system of claim 9 , wherein:

the ROSC recognition and post-ROSC circulation quality evaluation apparatus comprises frequency-domain recognition logic, said frequency-domain recognition logic determining whether there is ROSC in the CPR process by detecting time-varying features of spectral peaks of the sampled signals in the frequency domain.

11. The ROSC feedback system of claim 8 , wherein: the frequency-domain recognition logic determines that there is ROSC when spectral peaks are recognized continuously at different frequencies or significant amplitude change is recognized for spectral peaks within a certain period.

12. The system of claim 8 , wherein the ROSC recognition and post-ROSC circulation quality evaluation apparatus comprises further comprises time-domain recognition logic provided for determining whether there is ROSC in the CPR process by detecting time envelope features of sampled signals in the time domain.

13. The ROSC feedback system of claim 12 , wherein: the time-domain recognition logic determines that there is ROSC when continuous and regular envelope features are recognized.

14. The ROSC feedback system of claim 12 , wherein:

the time-domain recognition logic determines that there is ROSC when continuous and regular envelope features are recognized, and determines whether there is ROSC in the CPR process by detecting time envelope features of sampled signals in the time domain.

15. A device for real-time recognition of restoration of spontaneous circulation (ROSC) in a cardio-pulmonary resuscitation (CPR) process, comprising:

a signal acquisition apparatus comprising a sensor for blood oxygen saturation

detection based upon light absorption and acquiring pulse oximetry waveform signals of a patient, at least one pulse oximetry waveform signal comprising a manual compression waveform signal and a spontaneous circulation waveform signal; and

a signal analysis apparatus comprising a time-domain recognition logic provided for analyzing the pulse oximetry waveform signals in a frequency domain to identify a first frequency and a first amplitude for the manual compression waveform signal and a second frequency and a second amplitude for the spontaneous circulation waveform signal to determine whether there is ROSC in the CPR process by detecting time-varyinq features of spectral peaks of the sampled signals including the second frequency and the second amplitude of the spontaneous circulation waveform signal in the frequency domain;

said time-domain recognition logic provided for determining whether there is ROSC in the CPR process by detecting a time envelope of the signals in the time domain and determining that there is ROSC when continuous and regular envelope features are recognized.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2014
From: XU, JUN; YU, XUEZHONG; HAN, FEI; ZHENG, LIANGLIANG; ZHU, HUADONG; WANG, CHENG; ZHANG, XIAOCUI; LI, CHEN; YANG, JINGMING; JIN, XINGLIANG; FU, YANGYANG; YAO, DONGQI
To: PEKING UNION MEDICAL COLLEGE HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES; SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 033562/0554 →
Priority Claims (1)
CN 2013 1 0685817 · Dec 16, 2013 · national
Continuity (1)
Related Publication 20150164339A1 · Jun 18, 2015