IP Library Granted Patent US 10,330,600
Granted Patent B2
US 10,330,600 · App. 15/398,134 · Granted Jun 25, 2019

Plasmonic-magnetic bifunctional nanotubes for biological applications

Inventors: Donglei Fan (Austin, TX); Xiaobin Xu (Austin, TX)
Assignee: Board of Regents, The University of Texas System
G01N21/658B82Y15/00B82Y25/00G01N33/5432G01N33/552H01F1/0063H01F1/0072A61K9/0092Y10T428/2956
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Quick Facts
Patent No.
US 10,330,600
App. No.
15/398,134
Granted
Jun 25, 2019
Kind
B2
Abstract

The present invention includes nanotubes or rods, methods and arrays using plasmonic-magnetic bifunctional nanotubes or rods comprising: one or more silica nanotubes or rods; one or more nanomagnets embedded in a portion of the silica nanotubes or rods; and plasmonic metal nanoparticles uniformly coating in or on at least a portion of the surface of the nanomagnets and the silica nanotubes surface-coated.

Claims (17)

1. A plasmonic-magnetic bifunctional nanocapsule comprising:

a silica nanotube having a metallic rod embedded therein; and

metallic nanoparticles coated on a surface of the silica nanotube.

2. The nanocapsule of claim 1 , wherein the silica nanotube shell thickness is from 70 nm to 150 nm.

3. The nanocapsule of claim 1 , wherein the nanocapsule has a diameter from 100 nm to 0.01 cm.

4. The nanocapsule of claim 1 , wherein the metallic nanoparticles comprise at least one of silver, gold, cobalt, rhodium, iridium, copper, platinum, or palladium.

5. The nanocapsule of claim 1 , wherein the metallic rod comprises nickel, platinum, silver, or gold.

6. The nanocapsule of claim 1 , wherein the metallic rod consists of nickel.

7. The nanocapsule of claim 1 , wherein the metallic rod is a segmented metallic rod.

8. The nanocapsule of claim 7 , wherein the segmented metallic rod comprises segments of silver or gold, and segments of nickel.

9. The nanocapsule of claim 1 , wherein the metallic nanoparticles are coated on the outer surface of the silica nanotube.

10. The nanocapsule of claim 9 , wherein the entire outer surface of the silica nanotubes is coated with metallic nanoparticles.

11. The nanocapsule of claim 1 , wherein a portion of the silica nanotube is hollow.

12. The nanocapsule of claim 11 , wherein the metallic nanoparticles are coated on the outer and the inner surface of the silica nanotube.

13. The nanocapsule of claim 1 , wherein the silica nanotube shell thickness is from 100 nm to 1 μm.

14. The nanocapsule of claim 1 , further comprising an active agent.

15. The nanocapsule of claim 14 , wherein the nanocapsule is surface functionalized to bind the active age.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2017
From: FAN, DONGLEI; XU, XIAOBIN
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 043775/0934 →
CONFIRMATORY LICENSE Recorded Feb 17, 2017
From: UNIVERSITY OF TEXAS, AUSTIN
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 041747/0199 →
Continuity (3)
Division 14296134 · Jun 4, 2014
Provisional Application 61830842 · Jun 4, 2013
Related Publication 20170115227A1 · Apr 27, 2017