Over-patch having improved compatibility and a long adhesion duration and method for producing said over-patch
The invention relates to a medical product for a fastening duration of at least 7 days having good skin compatibility. The medical product includes a central adhesive compartment ( 3 ) and an over-patch. The over-patch is free of active ingredients and is formed from a water-vapor-permeable back layer ( 1 ) and an adhesive polymer layer ( 2 ) that is free of active ingredients. The invention further relates to a method for the production of the foregoing medical product, and to kits of parts containing laminates of layers 1 and 2.
1. A medical product comprising (1) a central compartment and (2) an active-ingredient-free overplaster,
wherein said medical product is a diagnostic agent, and
wherein said overplaster comprises
a) a water vapor-permeable backing layer and
b) a pressure-sensitive, acting-ingredient-free polymer layer, and
wherein said central compartment comprises a diagnostic apparatus and is pressure-sensitively adhered to a releasable release liner such that said central compartment can be applied directly to the skin after removal of said releasable release liner,
said overplaster fixes the central compartment and overhangs said central compartment on all sides and the active-ingredient-free polymer layer comprises non-amine-resistant, highly water vapor-permeable polysiloxanes, polyacrylates or vinyl acetate-acrylate copolymers without free acid groups or with an acid number of less than 1, styrene-isoprene-styrene block copolymers present in combination with at least one of hydrogenated hydrocarbon resins and oils, or styrene-butadiene-styrene block copolymers present in combination with at least one of hydrogenated hydrocarbon resins and oils.
2. A medical product comprising (1) a central compartment and (2) an active-ingredient-free overplaster,
wherein said medical product is a cannula fixing plaster, and
wherein said overplaster comprises
a) a water vapor-permeable backing layer and
b) a pressure-sensitive, active-ingredient-free polymer layer, and
wherein said central compartment comprises a cannula and is pressure-sensitively adhered to a releasable release liner such that said central compartment can be applied directly to the skin after removal of said releasable release liner,
said overplaster fixes the central compartment and overhangs said central compartment on all sides and the active-ingredient-free polymer layer comprises non-amine-resistant, highly water vapor-permeable polysiloxanes, polyacrylates or vinyl acetate-acrylate copolymers without free acid groups or with an acid number of less than 1, styrene-isoprene-styrene block copolymers present in combination with at least one of hydrogenated hydrocarbon resins and oils, or styrene-butadiene-styrene block copolymers present in combination with at least one of hydrogenated hydrocarbon resins and oils.
3. The medical product as claimed in claim 1 , wherein the active-ingredient-free polymer layer further comprises a neutral oil as compatibilizer, and the concentration of said neutral oil is 0 to 5% (w/w) based on the layer dry weight.
4. The medical product as claimed in claim 1 , wherein the active-ingredient-free polymer layer comprises 0.5 to 5% (w/w) of dexpanthenol, based on the layer dry weight.
5. The medical product as claimed in claim 1 , wherein the active-ingredient-free polymer layer comprises non-amine-resistant polysiloxane polymers in which, after polycondensation of a resin fraction and polydimethylsiloxanol groups, remaining silanol groups that are still free have not been capped by methyl groups.
6. The medical product as claimed in claim 1 , wherein the active-ingredient-free polymer layer further comprises silicone oil, and the concentration of said silicone oil is 0 to 4% (w/w) based on the layer dry weight.
7. The medical product as claimed in claim 1 , wherein the backing layer comprises a bidirectional elastic fabric permeable to water vapor.
8. The medical product as claimed in claim 7 , wherein the fabric is a polyester fabric.
9. The medical product as claimed in claim 1 , wherein the styrene-isoprene-styrene (SIS) block copolymer or the styrene-butadiene-styrene (SBS) block copolymer is selected as a polymer in the active-ingredient-free polymer layer, and wherein the SIS block polymer or the SBS block copolymer is present in combination with the following oil: liquid paraffin.
10. The medical product as claimed in claim 2 , wherein the active-ingredient- free polymer layer further comprises a neutral oil as compatibilizer, and the concentration of said neutral oil is 0 to 5% (w/w) based on the layer dry weight.
11. The medical product as claimed in claim 2 , wherein the active-ingredient-free polymer layer comprises 0.5 to 5% (w/w) of dexpanthenol, based on the layer dry weight.
12. The medical product as claimed in claim 2 , wherein the active-ingredient-free polymer layer further comprises silicone oil, and the concentration of said silicone oil is 0 to 4% (w/w) based on the layer dry weight.
13. The medical product as claimed in claim 2 , wherein the backing layer comprises a bidirectional elastic fabric permeable to water vapor.
14. The medical product as claimed in claim 13 , wherein the fabric is a polyester fabric.
15. The medical product as claimed in claim 2 , wherein the styrene-isoprene-styrene (SIS) block copolymer or the styrene-butadiene-styrene (SBS) block copolymer is selected as a polymer in the active-ingredient-free polymer layer, and wherein the SIS block polymer or the SBS block copolymer is present in combination with the following oil: liquid paraffin.