IP Library › Granted Patent US 10,335,476
Granted Patent B2
US 10,335,476 · App. 14/919,494 · Granted Jul 2, 2019

Vaccine to protect against

Inventors: Sunil Thomas (Dickinson, TX); David H. Walker (Galveston, TX)
Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
A61K39/0233A61K2039/545A61K2039/55566
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Quick Facts
Patent No.
US 10,335,476
App. No.
14/919,494
Granted
Jul 2, 2019
Kind
B2
Abstract

Certain embodiments are direct to a vaccine composition comprising an immunizing amount of an Ehrlichia sonicate, wherein the Ehrlichia sonicate elicits a protective physiologic response. In certain aspects the Ehrlichia is one or more of E. canis, E. chaffeensis, E. muris, E. ruminantium, E. ewingii , and E. ovis.

Claims (2)

1. A vaccine composition comprising an immunizing amount of an Ehrlichia muris sonicate, wherein the Ehrlichia muris sonicate elicits an antibody independent protective immune response within 7 days of Ehrlichia muris challenge.

2. The vaccine composition of claim 1 , further comprising an adjuvant.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2016
From: THOMAS, SUNIL; WALKER, DAVID H.
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 037795/0817 →
Continuity (2)
Provisional Application 62066461 · Oct 21, 2014
Related Publication 20160106825A1 · Apr 21, 2016