IP Library Granted Patent US 10,364,473
Granted Patent B2
US 10,364,473 · App. 15/257,423 · Granted Jul 30, 2019

Fast diagnosis and personalized treatments for acne

Inventors: Huiying Li (Los Angeles, CA); Shuta Tomida (Santa Monica, CA); Robert L. Modlin (Sherman Oaks, CA); Jeffery F. Miller (Santa Monica, CA); Sorel T. Fitz-Gibbon (Los Angeles, CA)
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
C12Q1/689A61K35/741A61K35/76A61K39/0208A61K39/05C12N7/00C12Q1/6883C12Q1/701C12N2795/00032C12Q2600/112C12Q2600/156C12Q2600/16
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Quick Facts
Patent No.
US 10,364,473
App. No.
15/257,423
Granted
Jul 30, 2019
Kind
B2
Abstract

Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne include administering an effective amount of a drug specifically targeting RT4, RT5, RT7, RT8, RT9, or RT10, such as small molecules, antisense molecules, siRNAs, biologics, antibodies, phages, vaccines, or combination thereof.

Claims (8)

1. A method for treating acne in a subject in need thereof, comprising: administering an effective amount of a composition comprising an RT6 strain of P. acnes to the subject.

2. The method of claim 1 , wherein the strain has at least 99% homology to SEQ ID NO: 6.

3. The method of claim 2 , wherein the strain has at least 100% homology to SEQ ID NO: 6.

4. The method of claim 1 , wherein the strain has at least 95% homology to SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, or SEQ ID NO: 54.

5. The method of claim 4 , wherein the strain has at least 99% homology to SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, or SEQ ID NO: 54.

6. The method of claim 5 , wherein the strain has at least 100% homology to SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, or SEQ ID NO: 54.

7. The method of claim 1 , wherein the composition is formulated for topical application.

8. The method of claim 7 , wherein the composition is formulated as a cream.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 29, 2018
From: MODLIN, ROBERT L.; MILLER, JEFFERY F.; FITZ-GIBBON, SOREL T.
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 047686/0560 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2016
From: LI, HUIYING; TOMIDA, SHUTA
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 039834/0351 →
Continuity (3)
Division 14385576
Provisional Application 61612290 · Mar 17, 2012
Related Publication 20170058328A1 · Mar 2, 2017
Cited By (1)
US 12,502,424