Sterilization and filtration of peptide compositions
Methods and devices for sterilizing viscous peptide compositions which have shear thinning rheological properties at high concentrations.
1. A method for sterilizing a liquid peptide composition whose sequence comprises a series of repeating units of IEIK as set forth in SEQ ID NO:6 comprising subjecting the liquid peptide composition to autoclave treatment.
2. The method of claim 1 , wherein the method does not involve sterilizing filtration.
3. A method for sterilizing a liquid peptide composition whose sequence comprises a series of repeating units of IEIK as set forth in SEQ ID NO:6 comprising subjecting the liquid peptide composition to heat treatment performed at about 121° C. for about 25 minutes.
4. The method of claim 1 , wherein the liquid peptide composition has a concentration within the range of about 0.01% to about 10%.
5. The method of claim 1 , wherein the liquid peptide composition comprises IEIK13 as set forth in SEQ ID NO: 3.
6. The method of claim 1 , wherein the method does not degrade the liquid peptide composition.
7. The method of claim 3 , wherein the liquid peptide composition has a concentration within the range of about 0.01% to about 10%.
8. The method of claim 3 , wherein the liquid peptide composition comprises IEIK13 as set forth in SEQ ID NO: 3.
9. The method of claim 3 , wherein the method does not degrade the liquid peptide composition.