Compounds useful for inhibiting metastasis from cancer and methods using same
The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX 3 CR1 or fractalkine antagonist.
1. A compound of Formula (IX):
R A —R B (IX)
wherein:
R A is selected from the group consisting of:
and
R B is selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound of Formula (IX) and at least one pharmaceutically acceptable carrier, wherein the compound of Formula (IX) is:
R A —R B (IX)
wherein:
R A is selected from the group consisting of:
and
R B is selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.