IP Library Granted Patent US 10,464,967
Granted Patent B2
US 10,464,967 · App. 14/360,384 · Granted Nov 5, 2019

Non-hormonal steroid modulators of NF-κβ for treatment of disease

Inventors: John M. McCall (Boca Grande, FL); Eric Hoffman (Kensington, MD); Nagaraju (Raju) Kanneboyina (Kensington, MD); Jesse Damsker (Washington, DC)
Assignee: ReveraGen BioPharma, Inc.
C07J7/003A61K31/573A61K31/58
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Quick Facts
Patent No.
US 10,464,967
App. No.
14/360,384
Granted
Nov 5, 2019
Kind
B2
Abstract

The present invention relates to compounds and methods which may be useful as treatments of diseases.

Claims (4)

1. A method of reducing the symptoms of astrocytoma in a patient in need thereof, comprising the administration, to the patient, of a therapeutically effective amount of a compound having the structural formula:

2. The method of claim 1 , wherein the symptom is inflammation.

3. The method of claim 1 , wherein the symptom is edema.

4. The method of claim 1 , wherein the astrocytoma is a glioblastoma.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 30, 2024
From: REVERAGEN BIOPHARMA INC
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066378/0800 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2015
From: MCCALL, JOHN M.; HOFFMAN, ERIC; KANNEBOYINA, NAGARAJU; DAMSKER, JESSE
To: REVERAGEN BIOPHARMA, INC.
Reel/Frame 034863/0966 →
Continuity (2)
Provisional Application 61564701 · Nov 29, 2011
Related Publication 20150011519A1 · Jan 8, 2015
Cited By (1)
US 12,201,639