System for the transdermal delivery of active ingredient
The invention relates to a transdermal therapeutic system (TTS) for delivering pharmaceutical active ingredients. The TTS includes a cover layer and at least one active-ingredient-containing carrier material. At least one retaining element is located between the active-ingredient-containing carrier material and the cover layer, with the retaining element fixing the active-ingredient-containing carrier material onto the cover layer. The invention further relates to a method for fastening an active-ingredient-containing carrier material to a cover layer of a TTS in the presence of hook-and-loop strip segments and the use of a hook-and-loop strip in transdermal or iontophoretic administration of pharmaceutical or therapeutic active ingredients to patients.
1. A method of attaching an active-containing carrier material to a TTS backing layer in the presence of hook and loop tape segments, wherein the active-containing carrier material is liquid saturated and the method comprises
opening an upward side of a package containing the active-containing carrier material by removing a closure film from the package;
approximating the active-containing carrier material in the opened package to the backing layer and the hook and loop tape segments disposed thereon,
then pressing the package together with the active-containing carrier material present therein against the hook and loop tape segments on the backing layer,
thereafter releasing and removing the package and leaving the active-containing carrier material secured to the hook and loop tape segments and to the backing layer.