IP Library Granted Patent US 10,518,007
Granted Patent B2
US 10,518,007 · App. 15/510,592 · Granted Dec 31, 2019

Blood component separation device

Inventor: Shigeyuki Kimura (Shizuoka, JP)
Assignee: Terumo Kabushiki Kaisha
A61M1/0245A61M1/0209A61M1/0236A61M1/0272A61M1/3693A61M1/385B04B5/0442B04B11/02C12N5/0634C12N5/0644A61M1/3643A61M2202/0427A61M2205/3337A61M2230/207
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Quick Facts
Patent No.
US 10,518,007
App. No.
15/510,592
Granted
Dec 31, 2019
Kind
B2
Abstract

A blood component separation device for separating a plurality of blood components from blood sampled from a blood donor, and collecting platelets, includes: an donor calculation unit that calculates a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood, and calculates a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate, wherein the operating unit sets the predicted platelet recovery rate calculated from any the hematocrit value and any the platelet concentration to be smaller by a predetermined value α when the blood donor is female than that when the blood donor is male.

Claims (26)

1. A method for collecting platelets with a blood component separation device for separating a plurality of blood components from blood sampled from a blood donor comprising:

calculating a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood;

calculating a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate; and

setting the predicted platelet recovery rate calculated from the hematocrit value and the platelet concentration to be smaller by a predetermined value when the blood donor is female than that when the blood donor is male, thereby increasing a number of collection cycles for a female donor as compared to a male donor having the same platelet concentration.

2. The method according to claim 1 , wherein

the predetermined value increases as the recommended processing amount of the blood increases.

3. The method according to claim 2 , wherein

a) a centrifugal separation step of introducing the blood into a centrifuge, and separating the blood into a plurality of blood components;

b) a circulation flow step of introducing plasma among the separated blood components into the centrifuge together with the blood;

c) a circulation and acceleration step of introducing only plasma into the centrifuge while stopping feeding of the blood into the centrifuge after the circulation flow step, allowing plasma to further circulate for a predetermined time, and then accelerating a circulation velocity, to separate and collect platelets by the centrifuge, and

d) a blood returning step of returning blood components that have not been collected to the blood donor after the circulation and acceleration step, are conducted,

the steps a) to d) are conducted as one cycle, and

the operation unit calculates a recommended cycle number as the recommended processing amount of the blood.

4. The method according to claim 1 , wherein

by rotating the separation vessel about an axial center while feeding the blood into a separation vessel, the blood in the separation vessel is separated into a plurality of blood components, and platelets are collected from the plurality of separated blood components.

5. The method according to claim 1 ,

wherein

a) a centrifugal separation step of introducing the blood into a centrifuge, and separating the blood into a plurality of blood components;

b) a circulation flow step of introducing plasma among the separated blood components into the centrifuge together with the blood;

c) a circulation and acceleration step of introducing only plasma into the centrifuge while stopping feeding of the blood into the centrifuge after the circulation flow step, allowing plasma to further circulate for a predetermined time, and then accelerating a circulation velocity, to separate and collect platelets by the centrifuge, and

d) a blood returning step of returning blood components that have not been collected to the blood donor after the circulation and acceleration step, are conducted,

the steps a) to d) are conducted as one cycle, and

the operation unit calculates a recommended cycle number as the recommended processing amount of the blood.

6. The method according to claim 1 ,

wherein the predetermined value increases as the recommended processing amount of the blood increases; and

wherein by rotating the separation vessel about an axial center while feeding the blood into the circular separation vessel, the blood in the separation vessel is separated into a plurality of blood components, and platelets are collected from the plurality of separated blood components.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2017
From: KIMURA, SHIGEYUKI
To: TERUMO KABUSHIKI KAISHA
Reel/Frame 041544/0714 →
Priority Claims (1)
JP 2014-191403 · Sep 19, 2014 · national
Continuity (1)
Related Publication 20170296718A1 · Oct 19, 2017
Cited By (3)
US 12,214,366 US 12,257,378 US 12,478,712