Flowable concentrated phospholipid krill oil composition
The present invention is related to methods of making crustacean oil compositions. In particular, the crustacean oil compositions are krill oil compositions. In some embodiments, the krill oil compositions are concentrated in phospholipids. These concentrated phospholipid krill oil compositions have a sufficient flowability to permit successful encapsulation at phospholipid concentrations that is currently unattainable in the art. Such phospholipid krill oil compositions are capable of encapsulation even though they may have a phospholipid concentration ranging between approximately 60%-99% and a viscosity ranging between 100,000-3,000,000 cP. Such concentrated phospholipid krill oil compositions may be created using a small molecule organic solvent/water extraction mixture and/or sub-critical or super-critical fluid extraction at low temperatures followed by a drying process to remove water and organic solvent (e.g., for example, ethanol).
1. A method comprising:
a) providing;
i) a hill oil composition comprising phospholipids ranging between 60%-99% (w/w), water and an organic solvent;
ii) a means for gentle drying; and
iii) an empty capsule;
b) gently drying the krill oil composition under conditions such that a gently dried semi-solid krill oil product comprising a water content between approximately 1-4% (w/w) and an organic solvent content less than 1% is created; and
c) filling the empty capsule with the gently dried semi-solid hill oil at a temperature of between 40° C. and a maximum of approximately 70° C.
2. The method of claim 1 , wherein said means for gentle drying is a lyophilizer.
3. The method of claim 1 , wherein said means for gentle drying is an oven.
4. The method of claim 1 , wherein said means for gentle drying is a nitrogen stream.
5. The method of claim 1 , wherein said filling is performed with a capsule filling machine.
6. The method of claim 1 , wherein said krill oil comprises a phospholipid content comprising phosphatidylcholine in a range of approximately 35-55% (w/w), alkyl acyl phosphatidylcholine in a range of approximately 3.0-6.0% (w/w), phosphatidylinositol in a range of approximately 0.5-0.9% (w/w), phosphatidylserine (PS) in a range of approximately 0.3-0.6%, lysophosphatidylcholine in a range of approximately 1.5-4.0%, lyso alkyl acyl phosphatidylcholine in a range of approximately 1.0-0.25%, phosphatidylethanolamine in a range of approximately 2.0-4.0%, alkyl acyl phosphatidylethanolamine in a range of approximately 0.25-1.25%, cardiolipin+Nacylphosphatidylethanolamine in a range of approximately 0.5-2.5%, lysophosphatidylethanolamine in a range of approximately 0.2-0.6%, and lyso alkyl acyl phosphatidylethanolamine of <0.1%.
7. The krill oil of claim 1 , wherein said krill oil is a collodial krill oil.
8. The krill oil of claim 1 , wherein said krill oil is a homogeneous krill oil.