IP Library › Granted Patent US 10,544,181
Granted Patent B2
US 10,544,181 · App. 15/755,393 · Granted Jan 28, 2020

Sugar derivative gelators

Inventors: Fumiyasu Ono (Fukuoka, JP); Koichiro Saruhashi (Funabashi, JP); Osamu Hirata (Funabashi, JP); Seiji Shinkai (Fukuoka, JP); Tatsuhiro Yamamoto (Fukuoka, JP)
Assignees: KYUSHU UNIVERSITY; INSTITUTE OF SYSTEMS, INFORMATION TECHNOLOGIES AND NANOTECHNOLOGIES; NISSAN CHEMICAL INDUSTRIES, LTD.
C07H9/04A61K8/042A61K8/60A61K47/26A61Q1/02C07B37/04C09K3/00C07C43/32C07C233/03
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,544,181
App. No.
15/755,393
Granted
Jan 28, 2020
Kind
B2
Abstract

A novel gelator including a sugar derivative; a gelator including a compound of Formula (1) or Formula (2): wherein R 1 is a linear or branched alkyl group having a carbon atom number of 9 to 20, a cyclic alkyl group having a carbon atom number of 13 to 20, or a linear or branched alkenyl group having a carbon atom number of 9 to 20, R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and R 3 and R 4 are hydroxy groups.

Claims (33)

1. A gelator comprising a compound of Formula (1) or Formula (2):

wherein

R 1 is a linear or branched alkyl group having a carbon atom number of 9 to 20, a cyclic alkyl group having a carbon atom number of 13 to 20, or a linear or branched alkenyl group having a carbon atom number of 9 to 20;

R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent; and

R 3 and R 4 are hydroxy groups.

2. The gelator according to claim 1 , wherein the compound of Formula (1) is a compound of Formula (3):

wherein R 1 and R 2 have the same meanings as defined in Formula (1).

3. The gelator according to claim 1 , wherein the compound of Formula (1) is a compound of Formula (4):

wherein R 1 and R 2 have the same meanings as defined in Formula (1).

4. A gel comprising:

the gelator as claimed in claim 1 ; and

a hydrophobic organic solvent, a hydrophilic organic solution, a hydrophobic organic solution, or an aqueous solution.

5. A gel comprising:

the gelator as claimed in claim 1 ;

a surfactant; and

a hydrophobic organic solvent, a hydrophilic organic solvent, water, a hydrophilic organic solution, a hydrophobic organic solution, or an aqueous solution.

6. The gel according to claim 4 , wherein the hydrophobic organic solvent is at least one solvent selected from the group consisting of vegetable oils, esters, silicone oils, and hydrocarbons.

7. The gel according to claim 4 , wherein the hydrophobic organic solution is a mixed solvent of water and the hydrophobic organic solvent wherein the hydrophobic organic solvent is at least one solvent selected from the group consisting of vegetable oils, esters, silicone oils, and hydrocarbons.

8. The gel according to claim 5 , wherein the hydrophilic organic solvent is at least one solvent selected from the group consisting of methanol, ethanol, 2-propanol, i-butanol, pentanol, hexanol, 1-octanol, iso-octanol, acetone, cyclohexanone, acetonitrile, dioxane, glycerol, propylene glycol, ethylene glycol, and dimethyl sulfoxide.

9. The gel according to claim 4 , wherein the hydrophilic organic solution is a mixed solvent of water and the hydrophilic organic solvent wherein the hydrophilic organic solvent is at least one solvent selected from the group consisting of methanol, ethanol, 2-propanol, i-butanol, pentanol, hexanol, 1-octanol, iso-octanol, acetone, cyclohexanone, acetonitrile, dioxane, glycerol, propylene glycol, ethylene glycol, and dimethyl sulfoxide.

10. The gel according to claim 4 , wherein fine particles are further dispersed in the gel.

11. The gelator according to claim 1 , wherein the gelator is a gelator of an ionic liquid.

12. A gel comprising:

the gelator as claimed in claim 1 , and

an ionic liquid.

13. A cosmetic base material or a medical base material comprising the gelator as claimed in claim 1 .

14. A method for producing the compound of Formula (1) or Formula (2) as claimed in claim 1 , the method being characterized by comprising:

producing the compound of Formula (1) or Formula (2) by annelation reaction of a compound of a formula R 1 —CHO (wherein R 1 is a linear or branched alkyl group having a carbon atom number of 9 to 20, a cyclic alkyl group having a carbon atom number of 13 to 20, or a linear or branched alkenyl group having a carbon atom number of 9 to 20) with glucose, mannose, galactose, or a derivative thereof in a single pot in the presence of triethyl orthoformate, DMF, or p-toluenesulfonic acid.

15. A compound of Formula (7) or Formula (8):

wherein

R 5 is a linear or branched alkyl group having a carbon atom number of 13 to 20, a cyclic alkyl group having a carbon atom number of 13 to 20, or a linear or branched alkenyl group having a carbon atom number of 13 to 18;

R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent; and

R 3 and R 4 are hydroxy groups.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2018
From: ONO, FUMIYASU; SARUHASHI, KOICHIRO; HIRATA, OSAMU; SHINKAI, SEIJI; YAMAMOTO, TATSUHIRO
To: KYUSHU UNIVERSITY; INSTITUTE OF SYSTEMS, INFORMATION TECHNOLOGIES AND NANOTECHNOLOGIES; NISSAN CHEMICAL INDUSTRIES, LTD.
Reel/Frame 045606/0764 →
Priority Claims (1)
JP 2015-165951 · Aug 25, 2015 · national
Continuity (1)
Related Publication 20180208618A1 · Jul 26, 2018
Cited By (1)
US 12,263,304