Built-in antimicrobial plastic resins and methods for making the same
A built-in and process-adaptive formulation of antimicrobial commodity thermoplastic resins with mixed compositions comprising of a polymer, a backbone linker, and a non-labile antifouling and biocompatible coupling agent which is melt-processable and enabled to be manufactured into finished products in the form of solid, monolith, tube, composite, fiber, film, sheet and varnish without the prerequisite of biocides or antimicrobial additives is disclosed. The said formulation is adapted to thermoforming and thermal curing processes including but not limited to melt compounding, spinning, extrusion, molding, compression foaming and drawing. The antimicrobial property is attributed to the persistent formation of a non-stick bacteria-repellent tethered layer in which the antifouling component of the said formulation is heterogeneously phase separated and/or surface migrated to the surface after product forming in order to minimize adsorption and/or colonization of bacteria.
1. A method for preparing an antimicrobial thermoplastic resin, comprising the steps of:
preparing an antimicrobial thermoplastic resin by either melt extruding a masterbatch and a basic plastic selected from the group consisting of a polyolefin and a polycarbonate,
wherein said antimicrobial thermoplastic is biocide-free and has bacterial-repellent properties; and
molding the antimicrobial thermoplastic resin into a finished article through a thermoforming process,
wherein said masterbatch comprises a co-polymer comprising a polystyrene repeating unit and a repeating unit represented by:
wherein PEG is polyethylene glycol;
a co-polymer comprising a polypropylene repeating unit and a repeating unit represented by:
a polymer comprising a polypropylene repeating unit crosslinked with an agent represented by:
a co-polymer comprising a polypropylene repeating unit and a repeating unit prepared by the reaction of a maleic anhydride-grafted olefin plastomer and polyethylene;
drying the masterbatch; and
pelletizing the masterbatch.
2. The method of claim 1 , wherein the thermoforming process is selected from a group consisting of spinning, extrusion, injection, compression, foaming and drawing.
3. The method of claim 1 , wherein the finished article is in a form selected from a group of solid, monolith, tube, composite, fiber, film, sheet and varnish.
4. The method of claim 1 , wherein the basic plastic is a thermoplastic and melt-processable plastic resin selected from a group consisting of polyethylene, polypropylene.
5. The method of claim 1 , wherein the step of preparing a masterbatch by grafting an antifouling reagent onto the intermediate is performed by a wet chemistry method.
6. An antimicrobial thermoplastic resin prepared by the method of claim 1 .
7. The method of claim 1 , wherein the masterbatch is present at a concentration of: 4.7% to 7.5% (m/m) in the antimicrobial thermoplastic resin.
8. The method of claim 7 , wherein the basic plastic is polyethylene, polypropylene, or polycarbonate.