Metabolism-improving agent comprising rare fatty acid
The present invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.
1. A method for the treatment of hyperlipidemia, comprising administering to a patient having hyperlipidemia an effective amount of a fatty acid selected from the group consisting of
13-hydroxy-cis-9,cis-15-octadecadienoic acid, 10-oxo-13-hydroxy-cis-15-octadecenoic acid, 13-oxo-cis-6,cis-9-octadecadienoic acid, 13-oxo-cis-9,cis-15-octadecadienoic acid, and 10,13-dioxo-cis-15-octadecenoic acid.
2. The method according to claim 1 , wherein an effective amount of 13-hydroxy-cis-9,cis-15-octadecadienoic acid is administered to the patient.
3. A method for promoting a PPAR activity, wherein the PPAR is PPARα or PPARγ, comprising administering to a patient having hyperlipidemia an effective amount of a fatty acid selected from the group consisting of
13-hydroxy-cis-9,cis-15-octadecadienoic acid, 10-oxo-13-hydroxy-cis-15-octadecenoic acid, 13-oxo-cis-6,cis-9-octadecadienoic acid, 13-oxo-cis-9,cis-15-octadecadienoic acid, and 10,13-dioxo-cis-15-octadecenoic acid.
4. The method according to claim 3 , wherein an effective amount of 13-hydroxy-cis-9,cis-15-octadecadienoic acid, is administered to the patient.
5. The method according to claim 3 , wherein an effective amount of 10-oxo-13-hydroxy-cis-15-octadecenoic acid is administered to the patient.
6. The method according to claim 3 , wherein an effective amount of 13-oxo-cis-6,cis-9-octadecadienoic acid is administered to the patient.
7. The method according to claim 3 , wherein an effective amount of 13-oxo-cis-9,cis-15-octadecadienoic acid is administered to the patient.
8. The method according to claim 3 , wherein an effective amount of 10,13-dioxo-cis-15-octadecenoic acid is administered to the patient.
9. The method according to claim 1 , wherein an effective amount of 10-oxo-13-hydroxy-cis-15-octadecenoic acid is administered to the patient.
10. The method according to claim 1 , wherein an effective amount of 13-oxo-cis-6,cis-9-octadecadienoic acid is administered to the patient.
11. The method according to claim 1 , wherein an effective amount of 13-oxo-cis-9,cis-15-octadecadienoic acid is administered to the patient.
12. The method according to claim 1 , wherein an effective amount of 10,13-dioxo-cis-15-octadecenoic acid is administered to the patient.