IP Library › Granted Patent US 10,555,883
Granted Patent B2
US 10,555,883 · App. 15/548,857 · Granted Feb 11, 2020

Oral care compositions and methods of use

Inventors: Paul Thomson (Piscatatway, NJ); Nihal Dogu (Dayton, NJ); Michael Prencipe (West Windsor, NJ); Amy Russo (Belle Mead, NJ); Hans Stettler (Basel, CH); Andre Michelle Morgan (Robbinsville, NJ)
Assignee: Colgate-Palmolive Company
A61K8/44A61K8/21A61K8/25A61K8/27A61K8/345A61K8/362A61K8/365A61Q11/00A61K2800/28A61K2800/92
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Quick Facts
Patent No.
US 10,555,883
App. No.
15/548,857
Granted
Feb 11, 2020
Kind
B2
Abstract

This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.

Claims (13)

1. An oral care composition comprising:

a. a basic amino acid in free or salt form, wherein the amino acid is L-arginine in an amount of about 1.5 wt. %;

b. zinc oxide and zinc citrate, wherein the zinc citrate is in an amount of about 0.5 wt. % and zinc oxide may be present in an amount of about 1.0 wt. % based on the total weight of the composition;

c. a fluoride source comprising stannous fluoride, wherein the stannous fluoride is present in an amount from 0.1 wt. % to 2 wt. % based on the total weight of the composition, and wherein the stannous fluoride provides about 750-7000 ppm fluoride; and

d. about 5% small particle silica, based on the total weight of the composition.

2. The oral care composition of claim 1 wherein the amino acid is arginine in free form.

3. The oral care composition of claim 1 wherein the amino acid is arginine partially or wholly in salt form.

4. The oral care composition of claim 1 , wherein the fluoride source further comprises at least one member selected from the group of: sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride (e.g., N′-octadecyltrimethylendiamine-N,N,N′-tris(2-ethanol)-dihydrofluoride), ammonium fluoride, titanium fluoride, hexafluorosulfate, and combinations thereof.

5. The composition of claim 1 , wherein stannous fluoride provides soluble fluoride in an amount of about 1000-5500 ppm.

6. The composition of claim 1 , wherein stannous fluoride provides soluble fluoride in an amount of about 5000 ppm.

7. The oral care composition of claim 1 further comprising:

d. about 39.2% glycerin based on the total weight of the composition.

8. The oral care composition of claim 1 , wherein the oral composition may be any of the following oral compositions selected from the group consisting of: a toothpaste or a dentifrice, a mouthwash or a mouth rinse, a topical oral gel, and a denture cleanser.

Continuity (2)
Provisional Application 62187801 · Jul 1, 2015
Related Publication 20180028423A1 · Feb 1, 2018