IP Library › Granted Patent US 10,561,709
Granted Patent B2
US 10,561,709 · App. 15/518,730 · Granted Feb 18, 2020

Methods and compositions of neuregulins for preventing, treating or delaying preserved ejection fraction cardiac failure

Inventor: Mingdong Zhou (Shanghai, CN)
Assignee: Zensun (Shanghai) Science & Technology, Co., Ltd.
A61K38/1883A61K9/0019A61K9/19A61K45/06
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Quick Facts
Patent No.
US 10,561,709
App. No.
15/518,730
Granted
Feb 18, 2020
Kind
B2
Abstract

Disclosed are the use of neuregulin proteins in preparing a medicine for preventing, treating or delaying preserved ejection fraction cardiac failure in mammals, and a method for using the medicine. Also provided in the present invention is a method for preventing, treating or delaying preserved ejection fraction cardiac failure in mammals, comprising using the medication containing the neuregulin proteins in a special population having the disease or being at risk of having the disease.

Claims (4)

1. A method for treating heart failure with preserved ejection fraction in a mammal, comprising administering neuregulin to the mammal, wherein the neuregulin is NRG-1.

2. The method of claim 1 , wherein the mammal is human.

3. A method for treating heart failure with preserved ejection fraction in a mammal, comprising administering neuregulin to the mammal, wherein the neuregulin comprises the amino acid sequence of SEQ ID NO: 1.

4. The method of claim 3 , wherein the mammal is human.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2017
From: ZHOU, MINGDONG
To: ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY, CO., LTD.
Reel/Frame 043868/0102 →
Priority Claims (1)
CN 2014 1 0550212 · Oct 17, 2014 · national
Continuity (1)
Related Publication 20170232068A1 · Aug 17, 2017
Cited By (4)
US 12,208,158 US 12,692,294 US 12,708,658 US 12,729,229