IP Library Granted Patent US 10,596,159
Granted Patent B2
US 10,596,159 · App. 15/751,901 · Granted Mar 24, 2020

Method and composition for treating cachexia and eating disorders

Inventors: Ramachandra Mukunda (Potomac, MD); Ranga Chelva Krishna (Englewood, NJ)
Assignee: India Globalization Capital, Inc.
A61K31/445A61K31/05A61K31/352A61K31/4418A61K36/185A61P3/04A61P43/00
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Quick Facts
Patent No.
US 10,596,159
App. No.
15/751,901
Granted
Mar 24, 2020
Kind
B2
Abstract

The invention provides treating cachexia and eating disorders in humans and veterinary animals by administering a composition including: (i) cyproheptadine (CYP); and (ii) a cannabis compound selected from the group of cannabidiol (CBD) and mixtures of CBD and up to 50% tetrahydrocannabinol (THC).

Claims (19)

1. A method for treating cachexia and eating disorders in humans and veterinary animals comprising administering to a patient in need thereof a composition comprising:

(i) cyproheptadine (CYP), wherein the CYP has a maximum dosage of about 0.2 mg/day for each kg of the patient body weight; and (ii) a cannabis compound selected from the group of cannabidiol (CBD) and mixtures of CBD and up to 50% tetrahydrocannabinol (THC).

2. The method of claim 1 wherein the cannabis compound is phytocannabinoids.

3. The method of claim 1 wherein CBD is synthetic CBD.

4. The method of claim 1 wherein THC is synthetic THC.

5. The method of claim 2 wherein the phytocannabinoids are compounded using heated gas or supercritical or subcritical CO2.

6. The method of claim 2 wherein the phytocannabinoids are derived from Cannabis sativa, indica, or hemp.

7. The method of claim 2 wherein CBD also contains minor or trace amounts of cannabinol (CBN), cannabichromene (CBC), cannabigerol (CBG), terpenoids, flavonoids, and other material found in Cannabis plants.

8. The method of claim 1 wherein the dosage of cannabis compound is from about 10 to about 300 mg/day.

9. The method of claim 1 wherein the dosage of CYP to cannabis compound is in the ratio of about 1:50 up to about 1:1500.

10. A composition comprising: (i) cyproheptadine (CYP), wherein the CYP has a maximum dosage of about 0.2 mg/day for each kg of the patient body weight; and (ii) a cannabis compound selected from the group of cannabidiol (CBD) and mixtures of CBD and up to 50% tetrahydrocannabinol (THC).

11. The composition of claim 10 wherein the cannabis compound is phytocannabinoids.

12. The composition of claim 10 wherein CBD is synthetic CBD.

13. The composition of claim 10 wherein THC is synthetic THC.

14. The composition of claim 11 wherein the phytocannabinoids are compounded using heated gas or supercritical or subcritical CO2.

15. The composition of claim 11 wherein the phytocannabinoids are derived from Cannabis sativa, indica, or hemp.

16. The composition of claim 11 wherein CBD also contains minor or trace amounts of cannabinol (CBN), cannabichromene (CBC), cannabigerol (CBG), terpenoids, flavonoids and other material found in Cannabis plants.

17. The composition of claim 10 wherein the amount of cannabis compound present is from about 10 to about 300 mg/day.

18. The composition of claim 10 wherein the ratio of CYP to cannabis compound is about 1:50 up to about 1:1500.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2018
From: MUKUNDA, RAMACHANDRA; KRISHNA, RANGA CHELVA
To: INDIA GLOBALIZATION CAPITAL, INC.
Reel/Frame 045629/0812 →
Continuity (2)
Provisional Application 62203968 · Aug 12, 2015
Related Publication 20180228788A1 · Aug 16, 2018
Cited By (2)
US 12,465,589 US 12,491,200