Intravascular catheter with positioning markers and method of placement

1. A method of positioning a dialysis catheter in a human comprising:

inserting into the human a dialysis catheter comprising:

a proximal end;

a distal end for insertion and terminating with a tip;

at least two lumens extending through the catheter from the proximal end to the tip, at least one lumen of the at least two lumens terminating at a distally facing opening in the distal tip;

a plurality of side facing openings in the distal end, the plurality of side facing openings in fluid communication with the at least one lumen terminating at the distally facing opening in the distal tip, the plurality of side facing openings located proximal to the distally facing opening, the plurality of side facing openings including a proximal-most side facing opening, the proximal-most side facing opening being the proximal-most side facing opening in the entire distal end; and

the proximal-most side facing opening associated with a radiopaque marker positioned proximally from and at a distance of 1 cm or less from the proximal-most side facing opening, the radiopaque marker radiographically distinguishing the location of the radiopaque marker from the rest of the distal end, wherein no side facing opening other than the proximal-most side facing opening associated with the radiopaque marker is radiographically distinguishable from the rest of the distal end, wherein the distance between the tip and the radiopaque marker defines a functional length in the range of about 1.5 cm to about 5 cm;

advancing the distal end of the catheter into the right atrium of the heart until the radiopaque marker is located at or adjacent to the junction of the right atrium and the superior vena cava, so that the entire functional length and all of the openings, including the proximal-most side facing opening, are located within the right atrium; and

assessing the position of the dialysis catheter by radiographically imaging the position of the radiopaque marker.

2. The method of claim 1 , wherein no location other than the approximate location of the proximal-most side opening is radiographically distinguishable from the rest of the distal end.

3. The method of claim 1 , wherein no other radiopaque marker is positioned between said radiopaque marker and said distal tip.

4. The method of claim 1 , wherein said distal tip comprises no radiopaque marker.

5. The method of claim 1 , wherein said radiopaque marker is positioned about 3 cm from said distal tip.

6. The method of claim 1 , further comprising performing dialysis on the human using said dialysis catheter.

7. The method of claim 1 , wherein advancing said distal tip of said dialysis catheter into the right atrium of the heart comprises:

accessing a vein with a needle;

advancing a wire through the needle and into the right atrium;

creating a subcutaneous tunnel from a vein access site to a catheter skin exit site;

advancing said distal tip of said dialysis catheter through the subcutaneous tunnel to the vein access site; and

further advancing said distal tip of the dialysis catheter into the right atrium until said radiopaque marker aligns with said junction of said right atrium and said superior vena cava.

8. The method of claim 1 , wherein the distal end of the dialysis catheter further comprises a second radiopaque marker that marks the tip.

9. The method of claim 8 , wherein the second radiopaque marker marks all or substantially all of the distal end.

10. The method of claim 8 , wherein the radiopaque marker that is discretely positioned proximally from and at a distance of 1 cm or less from the proximal-most side facing opening and the second radiopaque marker together form a radiographically distinguishable line that extends continuously from the proximal-most side facing opening to the tip.

11. The method of claim 1 , wherein the at least two lumens comprise two symmetric lumens each including a distally facing opening in the tip and a plurality of side facing openings that are proximal to the distally facing opening.

12. The method of claim 1 , wherein the functional length is sized such that the tip will not contact a wall or floor of the right atrium when the radiopaque marker is located at or adjacent to the junction of the right atrium and the superior vena.