Chondroitin complexes for transcutaneous absorption
The present invention relates to the use of chondroitin as a transdermal carrier and slow-release system for active ingredients in pharmaceutical and cosmeceutical compositions.
1. A method of transdermal or trans-mucosa delivery of a non-covalent complex of non-sulphated chondroitin having a molecular weight between 5 and 100 kDa determined by size exclusion chromatography and an active ingredient in a patient in need thereof, said method comprising
applying said complex on said skin or on said mucosa of said patient; and
obtaining said transdermal or transmucosa delivery of said complex, wherein said complex is absorbed through mucous membranes or skin and wherein said complex behaves as transdermal carrier and slow-release system for said active ingredient.
2. The method according to claim 1 , wherein the active ingredient is a non-steroidal or steroidal anti-inflammatory, an antitumoral, an antiviral, an antimicrobial, a diuretic, a contraceptive, an analgesic, a bronchodilator, a monoclonal antibody, an immunosuppressant, a vasoconstrictor or a vasodilator, an antioxidant, a soothing, moisturising or draining agent, a biostimulant, a radical scavenger, a wrinkle treatment agent, a hair growth compound or a bioactive peptide, or combinations thereof.
3. The method according to claim 1 , wherein said complex is administered topically, nasally, rectally or vaginally.
4. The method according to claim 1 wherein said complex is in the form of solutions, emulsions, gel, creams, sprays, suppositories, eyedrops, masks, patches, dressings and plasters.
5. The method according to claim 1 , wherein said non-sulphated chondroitin behaves as a transdermal carrier and slow-release system for said active ingredient.