Woven prosthesis and method for manufacturing the same

1. An implantable medical prosthesis configured as a generally tubular graft comprising:

a sidewall including a woven base comprising base warp yarns interwoven with weft yarn passes, at least a portion of the base warp yarns are woven in the warp direction to have a first frequency of interlacing, the woven base at least partially forming smaller and larger diameter portions of the prosthesis; and

one or more velour yarns forming part of both the smaller and larger diameter portions and interwoven with the weft yarn passes to have in the warp direction a second frequency of interlacing that is smaller than the first frequency of interlacing;

wherein in at least a portion of the larger diameter portion at least one of the one or more velour yarns that is interwoven with the weft yarn passes with the second frequency of interlacing is incorporated into the woven base and is interwoven with the weft yarn passes to have in the warp direction a frequency of interlacing that is larger than the second frequency of interlacing;

wherein a spacing between the base warp yarns and the at least one of the one or more velour yarns in the woven base in the larger diameter portion is maintained approximately the same as a spacing between the base warp yarns in the smaller diameter portion so that porosity of the sidewall is uniform throughout;

wherein a quantity of the base warp yarns and the one or more velour yarns is the same in the larger diameter portion as the smaller diameter portion; and

wherein the medical prosthesis has been subjected to a sterilization procedure.

2. The implantable medical prosthesis of claim 1 , wherein within the smaller diameter portion, the at least one of the one or more velour yarns is not incorporated into the woven base and does not exhibit a weave pattern consistent with the woven base.

3. The implantable medical prosthesis of claim 1 , wherein the larger diameter portion lies within a portion of the graft varying in diameter along a longitudinal axis of the graft and the smaller diameter portion lies within a portion of the graft having a generally uniform diameter.

4. The implantable medical prosthesis of claim 1 , wherein the larger and smaller diameter portions lie within a portion of the prosthesis varying with respect to diameter along a longitudinal axis of the graft.

5. The implantable medical prosthesis of claim 1 , wherein in at least a portion of the smaller diameter portion the one or more velour yarns exhibit a float that is entirely absent or smaller in the larger diameter portion.

6. The implantable medical prosthesis of claim 1 , wherein the base warp yarns and the one or more velour yarns are continuously woven between the smaller diameter portion and the larger diameter portion.

7. The implantable medical prosthesis of claim 1 , wherein the prosthesis comprises a secondary woven layer disposed over at least one of the smaller or larger diameter portions, and wherein a portion of a yarn forming the secondary layer is incorporated into the base layer of the larger diameter portion.

8. An implantable medical prosthesis comprising:

a tubular structure having a first open end and a second open end and a sidewall disposed therebetween, the tubular structure comprising a large diameter portion located along a length of the tubular structure but not at the first open end, and tapering towards the first open end;

wherein a portion of the tubular structure located between the first open end and the large diameter portion has a diameter smaller than the diameter of the large diameter portion;

wherein the sidewall of the tubular structure comprises a plurality of warp yarns continuously woven with a plurality of weft yarn passes between the first open end and the second open end;

wherein a portion of the tubular structure tapering between the large diameter portion and the first open end in a direction towards the first open end has an increase in the ratio of warp yarns woven as a velour layer than a base layer;

wherein a quantity of the warp yarns between the first open end and the second open end is the same;

wherein a spacing between the warp yarns woven as the base layer in the large diameter portion is approximately the same size as a spacing in the remaining portion of the tubular structure so that porosity of the sidewall is uniform throughout; and

a collagen or gel coating on the sidewall so that porosity of the sidewall with the coating is sufficient to provide for tissue ingrowth and is less than 5 milliliters per centimeter squared per minute at 120 mm Hg according to the Wesolowski method,

wherein the medical prosthesis has been subjected to a sterilization procedure.

9. The implantable medical prosthesis of claim 8 , wherein the base layer has 1/1 plain weave pattern, and the velour layer has a 5/1 velour weave pattern.

10. An implantable medical prosthesis configured as a generally tubular graft comprising:

a sidewall including a woven base comprising base warp yarns interwoven with weft yarn passes, at least a portion of the base warp yarns are woven in the warp direction to have a first frequency of interlacing, the woven base at least partially forming a smaller diameter portion and a larger diameter bulbous portion of the prosthesis; and

one or more velour yarns forming part of both the smaller diameter and larger diameter bulbous portions and interwoven with the weft yarn passes to have in the warp direction a second frequency of interlacing that is smaller than the first frequency of interlacing;

wherein in at least a portion of the larger diameter bulbous portion at least one of the one or more velour yarns that is interwoven with the weft yarn passes with the second frequency of interlacing is incorporated into the woven base and is interwoven with the weft yarn passes to have in the warp direction a frequency of interlacing that is larger than the second frequency of interlacing;

wherein a spacing between the base warp yarns and the at least one of the one or more velour yarns in the woven base in the larger diameter bulbous portion is maintained approximately the same as a spacing between the base warp yarns in the smaller diameter portion so that porosity of the sidewall is uniform throughout; and

wherein a quantity of the base warp yarns and the one or more velour yarns is the same in the larger diameter bulbous portion as the smaller diameter portion.

11. The implantable medical prosthesis of claim 10 , wherein within the smaller diameter portion, the at least one of the one or more velour yarns is not incorporated into the woven base and does not exhibit a weave pattern consistent with the woven base.

12. The implantable medical prosthesis of claim 10 , wherein the smaller diameter portion lies within a portion of the graft having a generally uniform diameter.

13. The implantable medical prosthesis of claim 10 , wherein the smaller diameter portion lies within a portion of the prosthesis varying with respect to diameter along a longitudinal axis of the graft.

14. The implantable medical prosthesis of claim 10 , wherein in at least a portion of the smaller diameter portion the one or more velour yarns exhibit a float that is entirely absent or smaller in the larger diameter bulbous portion.

15. The implantable medical prosthesis of claim 10 , wherein the base warp yarns and the one or more velour yarns are continuously woven between the smaller diameter portion and the larger diameter bulbous portion.

16. The implantable medical prosthesis of claim 10 , wherein the prosthesis comprises a secondary woven layer disposed over at least one of the smaller diameter portion or the larger diameter bulbous portion, and wherein a portion of a yarn forming the secondary layer is incorporated into the base layer of the larger diameter bulbous portion.

17. The implantable medical prosthesis of claim 10 , wherein the medical prosthesis has been subjected to a sterilization procedure.