IP Library › Granted Patent US 10,682,339
Granted Patent B2
US 10,682,339 · App. 16/415,141 · Granted Jun 16, 2020

Pharmaceutical compositions directly targeting FKBP52 for the treatment of prostate cancer and methods of using same

Inventors: Marc Cox (El Paso, TX); Artem Cherkasov (El Paso, TX)
Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; THE UNIVERSITY OF BRITISH COLUMBIA
A61K31/4184A61K45/06C07D235/28
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Quick Facts
Patent No.
US 10,682,339
App. No.
16/415,141
Granted
Jun 16, 2020
Kind
B2
Abstract

Embodiments of the current invention include methods and compositions for regulating the activity of hormone receptors.

Claims (6)

1. A method of inhibiting hormone receptor activation comprising administering to a subject in need of hormone receptor inhibition a compound having a chemical structure of Formula I

wherein the method further comprises administering chemotherapy or radiation treatments.

2. The method of claim 1 , wherein the hormone receptor is the androgen receptor.

3. The method of claim 1 , wherein the subject has prostatic hyperplasia or neoplasia.

4. The method of claim 3 , wherein the subject has prostate cancer.

5. A method of treating prostate cancer comprising administering to a subject having prostate cancer a compound having a chemical structure of Formula I

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 17, 2019
From: COX, MARC
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 049215/0217 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 17, 2019
From: CHERKASOV, ARTEM
To: THE UNIVERSITY OF BRITISH COLUMBIA
Reel/Frame 049215/0263 →
Continuity (3)
Division 15504562
Provisional Application 62039712 · Aug 20, 2014
Related Publication 20190269658A1 · Sep 5, 2019
Cited By (1)
US 12,351,560