IP Library Granted Patent US 10,694,947
Granted Patent B2
US 10,694,947 · App. 15/166,064 · Granted Jun 30, 2020

System and method for continuous monitoring of central nervous system diseases

Inventor: Jan Samzelius (San Francisco, CA)
Assignee: Neurametrix, Inc.
A61B5/0022A61B5/1118A61B5/4088A61B5/6897A61B5/7275A61B5/742G16H15/00A61B5/1124A61B5/486A61B5/7475G06F21/316
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Quick Facts
Patent No.
US 10,694,947
App. No.
15/166,064
Granted
Jun 30, 2020
Kind
B2
Abstract

A system and method for continuous monitoring of central nervous system diseases are provided in which typing cadence is used to measure cognitive function at a very granular level, providing hard, specific and detailed data to the neurologists about the central nervous system diseases. The system may also be used by a patient with a central nervous system disease to experiment with changes to diet, exercise and other things and test the effectiveness of those changes and patients can understand better why an unexpected improvement or worsening occurred.

Claims (25)

1. A system for continuous monitoring of central nervous system diseases, comprising:

a computing device having a keyboard and a typing cadence detector that:

detects a plurality of pieces of key event data generated from continuous typing of a document, the key event data generated during a sub-clinical typing activity and having a plurality of key combinations and one or more pieces of timing data about presses of the plurality of key combinations during a continuous typing sequence that describes a cadence of typing of keys on the keyboard; and

secures the key event data by removing an original clock stamp from each piece of key event data, and generates a plurality of pieces of typing cadence data from the secured key event data, the typing cadence data comprising time differentials between key press and key release actions determined from at least one of clock time data and one or more pieces of timing data for the plurality of pieces of key event data; and

a continuous monitoring apparatus having a processor that executes a plurality of lines of computer code so that the processor is configured to:

receive the plurality of pieces of typing cadence data for a particular patient at different times;

process the typing cadence data to generate a consistency measure by a coefficient of variance process;

generate data about a neurological disorder of a user using the generated consistency measure; and

generate a chart displaying the consistency measure of the user having the neurological disorder, the consistency measure of a second user that does not have a neurological disorder and an indicator showing a progress of the neurological disorder of the user.

2. The system of claim 1 , wherein the computing device is capable of displaying the generated chart for the user.

3. The system of claim 2 , wherein the user is one of a doctor and the patient.

4. The system of claim 1 , wherein the processor is further configured to generate an updated data report each time new typing cadence data for the patient is received.

5. A method for continuous monitoring of central nervous system diseases, comprising:

detecting, by a typing cadence detector located in a computer system having a keyboard, a plurality of pieces of key event data generated from continuous typing of a document, the key event data generated during a sub-clinical typing activity and having a plurality of key combinations and one or more pieces of timing data about presses of the plurality of key combinations during a continuous typing sequence that describes a cadence of typing of keys on the keyboard, securing the key event data by removing an original clock stamp from each piece of key event data and generating a plurality of pieces of typing cadence data based on the cadence of typing of keys, the typing cadence data comprising time differentials between key press and key release actions determined from at least one of clock time data and one or more pieces of timing data for the plurality of pieces of key event data;

receiving, at a continuous monitoring apparatus, the plurality of pieces of typing cadence data for a particular patient at different times; and

processing the typing cadence data to generate a consistency measure by a coefficient of variance process;

generating data using the generated consistency measure about a neurological disorder of a user; and

generating a chart displaying the consistency measure of the user having the neurological disorder, the consistency measure of a second user that does not have a neurological disorder and an indicator showing a progress of the neurological disorder of the user.

6. The method of claim 5 further comprising displaying, on the computing device, the generated chart for the user.

7. The method of claim 6 , wherein the user is one of a doctor and the patient.

8. The method of claim 5 , wherein generating the chart further comprises generating an updated chart each time new typing cadence data for the user is received.

9. The system of claim 1 , wherein the typing cadence data is a timing of a plurality of key presses of the keyboard during a time period.

10. The method of claim 5 , wherein the typing cadence data is a timing of a plurality of key presses of the keyboard during a time period.

11. The system of claim 1 , wherein the time differentials include a dwell time describing a time difference between a key press of a key and a release of the key by the user and a flight time describing a time difference between a key press of a first key and a key press of a second key.

12. The method of claim 5 , wherein the time differentials include a dwell time describing a time difference between a key press of a key and a release of the key by the user and a flight time describing a time difference between a key press of a first key and a key press of a second key.

Assignments (2)
NUNC PRO TUNC ASSIGNMENT Recorded Mar 8, 2022
From: NEURAMETRIX, INC. (A CALIFORNIA CORPORATION)
To: NEURAMETRIX, INC. (A NORTH CAROLINA COMPANY)
Reel/Frame 059199/0732 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2016
From: SAMZELIUS, JAN
To: NEURAMETRIX, INC.
Reel/Frame 039416/0991 →
Continuity (3)
Continuation In Part 14318477 · Jun 27, 2014
Provisional Application 62167766 · May 28, 2015
Related Publication 20160345908A1 · Dec 1, 2016