IP Library › Granted Patent US 10,696,676
Granted Patent B2
US 10,696,676 · App. 16/583,869 · Granted Jun 30, 2020

Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor

Inventors: Yam B. Poudel (Fremont, CA); Sanjeev Gangwar (Foster City, CA); Prasanna Sivaprakasam (Lawrenceville, NJ); Shoshana L. Posy (Highland Park, NJ)
Assignee: Bristol-Myers Squibb Company
C07D473/18A61P37/04
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,696,676
App. No.
16/583,869
Granted
Jun 30, 2020
Kind
B2
Abstract

Compounds having a structure according to formula (I) where R 1 , R 2 , and R 3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.

Claims (1)

1. A compound having a structure according to formula (Ia-01)

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2020
From: POUDEL, YAM B.; GANGWAR, SANJEEV; SIVAPRAKASAM, PRASANNA; POSY, SHOSHANA L.
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 051770/0924 →
Continuity (3)
Continuation 16103210 · Aug 14, 2018
Provisional Application 62546095 · Aug 16, 2017
Related Publication 20200024279A1 · Jan 23, 2020