IP Library › Granted Patent US 10,702,232
Granted Patent B2
US 10,702,232 · App. 16/368,774 · Granted Jul 7, 2020

Systems and methods for detecting complex networks in MRI image data

Inventor: Leanne Maree Williams (San Francisco, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61B6/501A61B5/055A61B5/165A61B5/168A61B5/4064A61B5/4088G06K9/0014G06T3/0093G06T7/0012G06T7/0014G06T7/0016A61B5/7267A61B2576/026G06K9/34G06K9/44G06T2207/10076G06T2207/10088G06T2207/10104G06T2207/20076G06T2207/20081G06T2207/30016
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,702,232
App. No.
16/368,774
Granted
Jul 7, 2020
Kind
B2
Abstract

Systems and methods for detecting complex networks in MRI image data in accordance with embodiments of the invention are illustrated. One embodiment includes an image processing system, including a processor, a display device connected to the processor, an image capture device connected to the processor, and a memory connected to the processor, the memory containing an image processing application, wherein the image processing application directs the processor to obtain a time-series sequence of image data from the image capture device, identify complex networks within the time-series sequence of image data, and provide the identified complex networks using the display device.

Claims (33)

1. A method for predicting and assigning effective treatment protocols, comprising:

obtaining a time-series sequence of image data of a patient's brain using a medical imaging device;

generating at least one neurological model, where the at least one neural model characterizes at least one neural circuit in the patient's brain;

assigning at least one biotype to the patient based on the neurological model;

generating a treatment database, where the treatment database associates biotypes with treatment protocols;

retrieving a treatment protocol from the treatment database based on the at least one assigned biotype.

2. The method for predicting and assigning effective treatment protocols of claim 1 , wherein treatment protocols in the treatment database comprise drug treatment.

3. The method for predicting and assigning effective treatment protocols of claim 1 , wherein treatment protocols in the treatment database comprise behavioral therapies.

4. The method for predicting and assigning effective treatment protocols of claim 1 , wherein treatment protocols in the treatment database comprise neuromodulation therapies.

5. The method for predicting and assigning effective treatment protocols of claim 1 , wherein the drug database further comprises efficacy metrics describing the efficacy of a treatment protocol with respect to at least one biotype.

6. The method for predicting and assigning effective treatment protocols of claim 5 , wherein the retrieved treatment protocol is associated with the efficacy metric signifying the highest likelihood of success of the treatment protocol for the individual based on the assigned at least one biotype.

7. The method for predicting and assigning effective treatment protocols of claim 1 , further comprising utilizing a machine learning model to generate efficacy metrics.

8. The method for predicting and assigning effective treatment protocols of claim 1 , further comprising providing a plurality of cognitive assessment scores representing the deviation of the individual's cognitive functions from an average cognitive function.

9. The method for predicting and assigning effective treatment protocols of claim 1 , further comprising providing a plurality of emotional assessment scores representing the deviation of the individual's cognitive functions from an average cognitive function.

10. The method for predicting and assigning effective treatment protocols of claim 1 , wherein the medical imaging system is a magnetic resonance imaging system.

11. A system for predicting and assigning effective treatment protocols, comprising:

a medical imaging device;

a processor; and

a memory comprising an image processing application, where the image processing application directs the processor to:

obtain a time-series sequence of image data of a patient's brain using the medical imaging device;

generate at least one neurological model, where the at least one neurological model characterizes at least one neural circuit in the patient's brain;

assign at least one biotype to the patient based on the neurological model;

generate a treatment database, where the treatment database associates biotypes with treatment protocols;

retrieve a treatment protocol from the treatment database based on the at least one assigned biotype.

12. The system for predicting and assigning effective treatment protocols of claim 11 , wherein treatment protocols in the treatment database comprise a plurality of drugs.

13. The system for predicting and assigning effective treatment protocols of claim 11 , wherein treatment protocols in the treatment database comprise a plurality of behavioral therapies.

14. The system for predicting and assigning effective treatment protocols of claim 11 , wherein treatment protocols in the treatment database comprise neuromodulation therapies.

15. The system for predicting and assigning effective treatment protocols of claim 11 , wherein the drug database further comprises efficacy metrics describing the efficacy of a treatment protocol with respect to at least one biotype.

16. The system for predicting and assigning effective treatment protocols of claim 15 , wherein the retrieved treatment protocol is associated with the efficacy metric signifying the highest likelihood of success of the treatment protocol for the individual based on the assigned at least one biotype.

17. The system for predicting and assigning effective treatment protocols of claim 11 , wherein the image processing application further directs the processor to generate efficacy metrics using a machine learning model to.

18. The system for predicting and assigning effective treatment protocols of claim 11 , wherein the image processing application further directs the processor to provide a plurality of cognitive assessment scores representing the deviation of the individual's cognitive functions from an average cognitive function using a display device.

19. The system for predicting and assigning effective treatment protocols of claim 11 , wherein the image processing application further directs the processor to provide a plurality of emotional assessment scores representing the deviation of the individual's cognitive functions from an average cognitive function using a display device.

20. The system for predicting and assigning effective treatment protocols of claim 11 , wherein the medical imaging system is a magnetic resonance imaging system.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2020
From: WILLIAMS, LEANNE MAREE
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 052360/0860 →
Continuity (7)
Continuation 15997631 · Jun 4, 2018
Continuation 15820338 · Nov 21, 2017
Provisional Application 62589452 · Nov 21, 2017
Provisional Application 62568676 · Oct 5, 2017
Provisional Application 62563611 · Sep 26, 2017
Provisional Application 62485196 · Apr 13, 2017
Related Publication 20190282191A1 · Sep 19, 2019
Cited By (1)
US 12,688,425